A translocation between chromosomes 9 and 22 (BCR-ABL) plays an important role in the development of

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Pediatric Infectious Disease Questions

Question 1 of 5

A translocation between chromosomes 9 and 22 (BCR-ABL) plays an important role in the development of

Correct Answer: B

Rationale: The BCR-ABL translocation (Philadelphia chromosome) is a hallmark of chronic myeloid leukemia.

Question 2 of 5

A boy with acute lymphoblastic leukemia is assigned to be of high risk group if he had got which of the following features?

Correct Answer: B

Rationale: Testicular involvement at diagnosis indicates high-risk ALL due to extramedullary spread.

Question 3 of 5

A 6-year- old girl presented with a 3-week history of abdominal distension, fever, and periorbital puffiness. Abdominal sonogram showed multiple intestinal related masses suggestive of lymphoma. Of the following, the BEST diagnostic procedure at this time is

Correct Answer: C

Rationale: Fine needle aspiration from the mass provides a definitive tissue diagnosis of lymphoma.

Question 4 of 5

If an intracranial lesion is suspected, the examination of choice is

Correct Answer: C

Rationale: MRI provides superior detail for diagnosing intracranial lesions compared to CT or other modalities.

Question 5 of 5

The MOST common clinical presentation for a 2-year- old girl with neuroblastoma is

Correct Answer: A

Rationale: An abdominal mass is the most frequent presenting sign of neuroblastoma due to adrenal or paravertebral origin.

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