ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
A TCR complex is comprised of the TCR, CD3 molecules, and which of the following CD3 chains?
Correct Answer: D
Rationale: The TCR complex includes two zeta ζ) chains as part of the CD3 signaling complex.
Question 2 of 5
Evidence is accumulating showing that polymorphism in the MHC may be advantageous. Homozygosity at HLA class I has been shown to be a(n) with respect to HIV/AIDS. Similarly, there is evidence that homozygosity at HLA class II the risk of hepatitis B virus infection persisting.
Correct Answer: D
Rationale: Homozygosity at HLA class I is a disadvantage for HIV/AIDS, and at class II increases hepatitis B persistence.
Question 3 of 5
Directly: some recognize nonpeptide phosphorylated lipids and carbohydrates; other recognize antigen that have not been processed
Correct Answer: C
Rationale: TCR γδ can recognize nonpeptide antigens and unprocessed antigens.
Question 4 of 5
The transporter associated with antigen presentation (TAP) the peptides to traverse the membrane bilayer of the endoplasmic reticulum and bind in the empty peptide-binding groove of nascent MHC molecules being synthesized in the endoplasmic reticulum.
Correct Answer: A
Rationale: TAP transports peptides into the ER for loading onto MHC Class I, not Class II.
Question 5 of 5
Protein antigens bound to complement component C3d can bind simultaneously to both and the BCR. This enables the co-receptor complex to cluster and crosslink with the BCR, inducing phosphorylation.
Correct Answer: C
Rationale: C3d binds to CD21 (CR2), linking the co-receptor to the BCR for enhanced signaling.