ATI RN
ATI Pharmacology Proctored Exam 2024 Quizlet Questions
Question 1 of 5
A severely immunocompromised female patient requires a blood transfusion. To prevent GVHD, the physician will order:
Correct Answer: C
Rationale: Irradiation of donor blood is a standard practice to prevent graft-versus-host disease (GVHD) in immunocompromised patients. Irradiation inactivates the donor's lymphocytes, preventing them from attacking the recipient's tissues. Diphenhydramine and acetaminophen are used to manage allergic reactions or fever but do not prevent GVHD. Administering the transfusion slowly does not address the risk of GVHD. Therefore, irradiation is the correct preventive measure.
Question 2 of 5
Most β blockers:
Correct Answer: A
Rationale: Most beta-blockers (e.g., propranolol, metoprolol) have half-lives of 3-10 hours, a true statement reflecting their typical duration, useful for dosing frequency. They have a large, not small, volume of distribution due to tissue penetration, so that's false. Many have good oral bioavailability, not poor, especially non-selective ones. Lipid solubility varies (e.g., propranolol is high, atenolol low), but many cross the BBB, causing CNS effects, though not universally true. They're often metabolized, not excreted unchanged. The half-life range is a key pharmacokinetic feature, guiding their use in hypertension or angina.
Question 3 of 5
A client has been prescribed testosterone. Which medication education should the nurse provide?
Correct Answer: A
Rationale: Testosterone patches require placement on hair-free skin to ensure proper adhesion and absorption, as hair can block drug delivery, reducing efficacy. Active areas like the thigh or arm are suitable if hairless and dry, contrary to avoidance claims-rotation across such sites is standard. Patches are changed daily, not weekly, for consistent hormone levels. Rash observation is key due to potential skin irritation, a common side effect. Hair-free placement is critical education, directly impacting bioavailability, unlike timing or site activity, which follow secondary guidelines, ensuring effective therapy for hypogonadism or related conditions.
Question 4 of 5
Which of the following are the four categories of pharmacokinetics?
Correct Answer: C
Rationale: Pharmacokinetics comprises absorption (entry to blood), distribution (to tissues), metabolism (chemical change), and excretion (removal)-standard categories tracking a drug's journey. Others mix processes or invent terms (e.g., interspersing), lacking precision. These four define the field, essential for dosing and effect.
Question 5 of 5
The patient has generalized anxiety disorder. He asks the nurse, 'Will I need medication for this? My neighbor is very nervous and he takes medication.' What is the best response by the nurse?
Correct Answer: D
Rationale: Medication for GAD (e.g., SSRIs) is warranted when anxiety disrupts daily function-quality of life-not universally or compared to others, a tailored approach. Meds as lifestyle is extreme. Initial meds then therapy assumes progression, not individual need. ‘Probably not' dismisses severity. Quality of life guides treatment, per guidelines.