A researcher who is interested in creating an anticholinergic agent that would be useful in patients with irritative bladder symptoms would be interested in targeting which of the following receptors?

A researcher who is interested in creating an anticholinergic agent that would be useful in patients with irritative bladder symptoms would be interested in targeting which of the following receptors?

In patients with Parkinson's disease, histologic studies suggest an imbalance in brain neurotransmitters. In contrast to normal individuals, the patients with Parkinson's disease have an abundance of which of the following neurons and associated neurotransmitters?

An 83-year-old woman with Parkinson's disease is currently being treated with carbidopa/levodopa, but her Parkinson's symptoms are worsening. She has normal liver function and no history of liver disease. The physician adds tolcapone to her regimen on tolcapone. How does tolcapone help in Parkinson's disease?

A 38-year-old man who is an inpatient in prison is serving a life sentence because of murder in the first degree. He is interested in suicide, but his only means is to overdose on coffee, which he has free access. The lethal dose of caffeine in grams and the estimated number of cups of coffee to achieve this is which of the following?

A 55-year-old woman with schizophrenia has been taking fluphenazine for 10 years to control her symptoms. At her regular 6-month checkup today, she complains of uncontrollable lip puckering movements. What is the next step the physician should take?