ATI RN
Safety Pharmacology Across the Lifespan ATI Quizlet Questions
Question 1 of 5
A researcher is developing a medication that selectively stimulates β₂-receptors without affecting any other receptors. As a result of such stimulation, which of the following effects is possible?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
A 17-year-old man is brought to the emergency department with severe right lower quadrant pain that he first felt around his umbilicus. His white blood cell count is 12,000/µl of blood. He is taken to the OR for emergent appendectomy. About an hour into the surgery, his body temperature spikes and CO₂ production rises uncontrollably. What was done differently in this patient’s procedure to lead to this outcome?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
A 72-year-old woman presents to her primary care physician with vision loss over the past year. She has noticed painless loss of her peripheral vision. Her peripheral vision has become darker. She is diagnosed with open-angle glaucoma and started on medication. She returns in 1 month and says her vision has improved, but now her blue eyes turned brown. What was the most likely medication given to treat her glaucoma?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A 24-year-old G1P1 woman presents to the emergency department days after giving birth to her first child. She lost a large amount of blood during birth. Her hemoglobin level is 12.5 g/dL (normal is 12.1 to 15.1 g/dL). Her gynecologist prescribes ferrous sulfate to help raise her hemoglobin levels. Which of the following is a common side effect of this medication?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Ten months after starting procainamide therapy for cardiac arrhythmias, a 56-year-old man develops arthritis and other symptoms consistent with drug-induced systemic lupus erythematosus. Results of a blood test are positive for antinuclear antibodies. This finding is consistent with which of the following genetic polymorphisms in drug metabolism?
Correct Answer: D
Rationale: Procainamide is metabolized by N-acetyltransferase (NAT2), and slow acetylators (E) have a genetic polymorphism leading to reduced acetylation. This results in accumulation of the parent drug, which is associated with an increased risk of drug-induced systemic lupus erythematosus (SLE), characterized by antinuclear antibodies, arthritis, and systemic symptoms. Debrisoquine 4-hydroxylase (CYP2D6) deficiency affects drugs like beta-blockers, not procainamide. COMT deficiency impacts catecholamine metabolism, irrelevant here. G6PD deficiency causes hemolysis, not SLE. Phenytoin hydroxylase relates to anticonvulsant metabolism.