A peripheral blood smear showing increase in numbers of neutrophils, band cells, basophils, eosinophils, and platelets is most suggestive

Correct Answer: C

Rationale: Step-by-step rationale: 1. Increased neutrophils, band cells, basophils, and platelets suggest myeloproliferative disorder. 2. Presence of eosinophils indicates a chronic phase as seen in chronic myelocytic leukemia. 3. Chronic myelocytic leukemia commonly presents with increased granulocytes and platelets. Summary: - A: Acute myeloid leukemia is characterized by blast cells, not mature granulocytes. - B: Acute lymphoid leukemia primarily affects lymphocytes, not myeloid cells. - D: Chronic lymphocytic leukemia involves lymphocytes, not myeloid cells like in the given case.

Correct Answer: B

Rationale: The correct answer is B: submandibular glands. Waldeyer's ring consists of the pharyngeal tonsil (adenoids), tubal tonsils, palatine tonsils (faucal tonsils), and lingual tonsils. The submandibular glands are salivary glands located outside of Waldeyer's ring. The other choices are incorrect because they are all part of Waldeyer's ring, which is a ring of lymphoid tissue located in the pharynx.

Correct Answer: C

Rationale: The correct answer is C: rheumatoid arthritis. In rheumatoid arthritis, there is chronic inflammation leading to elevated levels of ferritin (Fe) due to increased iron storage and a normal total iron-binding capacity (TIBC). This is because despite the increased iron stores, the body is unable to utilize it fully due to chronic inflammation. Incorrect choices: A: Thalassemia major would typically present with decreased TIBC due to increased iron absorption to compensate for the chronic anemia. B: Haemosiderosis would show elevated Fe but a decreased TIBC due to iron overload. D: Disseminated malignancy may show elevated Fe levels but typically with a decreased TIBC due to anemia of chronic disease.

Correct Answer: C

Rationale: The correct answer is C: clubbing. Plummer Vinson syndrome is characterized by the triad of dysphagia, iron deficiency anemia, and esophageal webs. Clubbing is not a typical feature of this syndrome. Angular stomatitis (A), splenomegaly (B), and post cricoid web (D) are all associated with Plummer Vinson syndrome. Angular stomatitis is due to iron deficiency anemia, splenomegaly can be present due to chronic anemia, and post cricoid web is a characteristic finding in the esophagus of patients with this syndrome.

Correct Answer: B

Rationale: Step 1: Cooley's anemia is another term for thalassemia major, a genetic disorder affecting hemoglobin production. Step 2: Thalassemia major results in severe anemia due to the body's inability to produce enough functional hemoglobin. Step 3: Sickle cell anemia (Choice A) is a different genetic disorder characterized by abnormal hemoglobin shape. Step 4: High ESR (Choice C) is a non-specific marker of inflammation, not specific to Cooley's anemia. Step 5: Aplastic anemia (Choice D) is a condition where the bone marrow does not produce enough blood cells, not specific to Cooley's anemia.