A patient with ulcerative colitis presents to your clinic with the classical signs of hyperglycemia. After doing all the necessary diagnostic workup, you diagnose the patient with type 2 Diabetes Mellitus. Which of the following antidiabetic drugs should NOT be given to this patient?

Correct Answer: D

Rationale: Miglitol is an alpha-glucosidase inhibitor, which is contraindicated in patients with inflammatory bowel disease (IBD) such as ulcerative colitis. This is because Miglitol causes undigested carbohydrates to accumulate in the intestines, which can exacerbate the inflammation and symptoms of IBD. Additionally, alpha-glucosidase inhibitors are also contraindicated in patients with renal failure. Therefore, Miglitol should not be prescribed to this patient, and alternative antidiabetic medications should be considered.

Correct Answer: D

Rationale: Budesonide is more effective when applied topically because it has poor cell membrane permeability, allowing it to remain localized at the site of application. This makes it particularly useful for treating severe eczema and other inflammatory skin conditions. Its localized action minimizes systemic side effects, making it a safer option for long-term topical use compared to other glucocorticoids.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.