A patient with pulmonary tuberculosis is prescribed the most effective antituberculosis antibiotic. Name this drug:

Questions 82

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McGraw Hill Microbiology Test Bank Questions

Question 1 of 9

A patient with pulmonary tuberculosis is prescribed the most effective antituberculosis antibiotic. Name this drug:

Correct Answer: C

Rationale: Rifampicin is the correct answer because it is a first-line antibiotic for treating pulmonary tuberculosis. It has excellent bactericidal activity and penetrates well into lung tissues where the infection is located. Rifampicin is also known for preventing the development of resistance. Tetracycline (A) and Furasolidone (B) are not commonly used for tuberculosis treatment. Bactrim (D) is a combination of sulfamethoxazole and trimethoprim, not effective for tuberculosis treatment.

Question 2 of 9

The nucleocapsid of viruses consists of

Correct Answer: B

Rationale: The correct answer is B because the nucleocapsid of viruses is composed of the genome (genetic material) and the capsid (protein coat). The genome contains the viral genetic information, while the capsid protects the genome and helps in viral attachment and entry into host cells. Choice A is incorrect because the envelope is not part of the nucleocapsid but surrounds the capsid in some viruses. Choice C is incorrect as spikes are surface proteins on the viral envelope, not part of the nucleocapsid. Choice D is also incorrect because the envelope is external to the capsid and genome in many viruses.

Question 3 of 9

4 days after a patient received a gunshot wound of the middle third of the thigh soft tissues his condition suddenly began deteriorating. There are complaints of bursting pain in the wound; pain increases during the last 12 hours. Edema of skin and hypodermic tissue quickly grows. Body temperature is 38,2oC, heart rate is 102/min. The wound edges gape, are dull in color; the muscles, viable as of day before, now protrude into the wound, look boiled, are dull in color, have dirty-grey coating and fall apart when being held with forceps. What infection has developed in the wound?

Correct Answer: A

Rationale: The correct answer is A: Anaerobic infection. The sudden deterioration, bursting pain, edema, foul appearance of wound, and presence of gas are indicative of gas gangrene caused by anaerobic bacteria like Clostridium perfringens. These bacteria thrive in low oxygen environments, such as deep wound tissues. The symptoms align with the classic presentation of gas gangrene, necessitating immediate surgical intervention. Choice B: Aerobic gram-negative, is incorrect because anaerobic bacteria, not aerobic gram-negative bacteria, are responsible for gas gangrene. Choice C: Putrid, is incorrect as it is a general term referring to foul-smelling decay and does not specify the type of infection. Choice D: Aerobic gram-positive, is incorrect as gas gangrene is typically caused by anaerobic bacteria, not aerobic gram-positive bacteria.

Question 4 of 9

Viral capsomeres are composed of subunits called

Correct Answer: B

Rationale: The correct answer is B: protomeres. Viral capsomeres are the building blocks of viral capsids, which are protein coats that enclose and protect the viral genetic material. These capsomeres are made up of smaller subunits called protomeres. Envelopes (A) refer to a lipid membrane surrounding some viruses, not the subunits of capsomeres. Capsids (C) are the protein coats that capsomeres make up, not the subunits themselves. Nucleoids (D) are found in bacterial cells and refer to the region where the genetic material is located, not the subunits of viral capsomeres.

Question 5 of 9

The causative agent of syphilis is:

Correct Answer: B

Rationale: The correct answer is B: Treponema pallidum. 1. Treponema pallidum is a spirochete bacterium known to cause syphilis. 2. Borrelia burgdorferi causes Lyme disease, not syphilis. 3. Leptospira interrogans causes leptospirosis, not syphilis. 4. Rickettsia rickettsii causes Rocky Mountain spotted fever, not syphilis. Therefore, Treponema pallidum is the causative agent of syphilis, making it the correct answer.

Question 6 of 9

Which of the following bacteria is responsible for causing bacterial meningitis?

Correct Answer: D

Rationale: The correct answer is D because all three bacteria (Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae) can cause bacterial meningitis. Neisseria meningitidis is a common cause of meningococcal meningitis, Haemophilus influenzae can cause H. influenzae meningitis, and Streptococcus pneumoniae is a leading cause of pneumococcal meningitis. Therefore, all of the above choices are correct. The other choices are incorrect because each of the bacteria listed can independently cause bacterial meningitis, so none of them alone can be the sole correct answer.

Question 7 of 9

Transcription of viral nucleic acid to mRNA is not needed in the case of:

Correct Answer: D

Rationale: The correct answer is D: Positive strand RNA viruses. These viruses have RNA genomes that can be directly translated by host ribosomes without the need for transcription. In contrast, single-strand DNA and double-strand DNA viruses require transcription to generate mRNA for translation. Choice A is incorrect as there is a correct answer. Choice B and C are incorrect because both single-strand DNA and double-strand DNA viruses require transcription for mRNA synthesis.

Question 8 of 9

A pregnant woman complains of vaginal mucosa irritation, itching and genital tracts secretion. Bacterioscopy of vaginal smears revealed large gram-positive oval oblong cells that form pseudomicelium. What is the most probable channel of infection?

Correct Answer: B

Rationale: The correct answer is B: Sexual transmission. The symptoms described are indicative of a vaginal yeast infection caused by Candida albicans. The presence of large gram-positive oval oblong cells forming pseudomycelium is characteristic of Candida infection. Sexual transmission is the most probable channel of infection as Candida can be transmitted through sexual contact. Endogenous infection (A) refers to infections originating from the body's own flora, which is not the case here. Contact infection (C) typically involves direct physical contact or fomite transmission, which is less likely in this scenario. Vector-borne transmission (D) involves transmission through vectors like mosquitoes or ticks, which is not relevant in this case.

Question 9 of 9

Beadlike chains of cocci formed after cell division along a single axis are called:

Correct Answer: B

Rationale: The correct answer is B: streptococci. This term refers to beadlike chains of cocci formed after cell division along a single axis. "Diplococci" (A) are pairs of cocci, "tetrads" (C) are groups of four cocci, and "sarcinae" (D) are cube-like groups of eight cocci. Streptococci is the most appropriate term for describing the specific arrangement mentioned in the question.

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