ATI RN
Microbiology An Evolving Science Test Bank Questions
Question 1 of 5
A patient with probable liver abscess was delivered to a surgical department. The patient for a long time had been on an assignment in an African country and had recurrent cases of gastrointestinal disturbance. What protozoan disease can it be?
Correct Answer: D
Rationale: The correct answer is D: Amebiasis. The patient's symptoms of gastrointestinal disturbance and liver abscess are indicative of an infection with Entamoeba histolytica, the protozoan parasite responsible for amebiasis. The patient's travel history to an African country also increases the likelihood of contracting this disease, as it is more prevalent in tropical regions. Toxoplasmosis (A) is primarily associated with exposure to cat feces, Leishmaniasis (B) is transmitted through sandfly bites, and Malaria (C) is caused by Plasmodium parasites transmitted through mosquito bites. Therefore, these options are incorrect given the patient's presentation and travel history.
Question 2 of 5
Granulomas containing lymphocytes and macrophages were detected during analysis of skin biopsy material. Among macrophages there are large cells with fat inclusions, which contain microorganisms in spheric packages (Virchow's cells). The following disease is based on the described type of hypersensitivity:
Correct Answer: C
Rationale: The correct answer is C: Tuberculosis. Granulomas with lymphocytes and macrophages containing Virchow's cells (large cells with fat inclusions containing microorganisms) are classic findings in tuberculosis. Leprosy (A) typically presents with granulomas but with different histopathological features. Syphilis (B) does not usually form granulomas in the skin. Rhinoscleroma (D) is a chronic bacterial infection characterized by nodular lesions but does not typically involve Virchow's cells as seen in tuberculosis.
Question 3 of 5
A 47-year-old male patient consulted a dentist about difficult mouth opening (lockjaw or trismus). The patient has a history of a stab wound of the lower extremity. What infection can be manifested by these symptoms?
Correct Answer: A
Rationale: The correct answer is A: Tetanus. Tetanus is caused by the bacterium Clostridium tetani, commonly found in soil, dust, and animal feces. The patient's history of a stab wound increases the risk of tetanus infection as the bacterium can enter the body through the wound. Tetanus infection can lead to symptoms such as lockjaw or trismus, which are characterized by muscle stiffness and difficulty opening the mouth. This is due to the neurotoxin produced by Clostridium tetani affecting the muscles. Summary of incorrect choices: B: Brucellosis is a bacterial infection transmitted from animals to humans through consumption of unpasteurized dairy products. It does not typically manifest with symptoms of lockjaw. C: Whooping cough (Pertussis) is a respiratory infection caused by Bordetella pertussis bacteria. It presents with severe coughing fits but does not cause lockjaw. D: Anaerobic wound infection
Question 4 of 5
What is a common characteristic of spore-forming bacteria?
Correct Answer: A
Rationale: The correct answer is A: Resistance to heat and dehydration. Spore-forming bacteria form spores as a survival mechanism in harsh conditions. These spores are highly resistant to heat and dehydration, allowing the bacteria to withstand extreme environments. This characteristic is essential for their long-term survival and ability to persist in unfavorable conditions. Choices B, C, and D are incorrect because not all spore-forming bacteria produce toxins, have flagella, or are capable of photosynthesis. These characteristics are not exclusive to spore-forming bacteria and do not define them as a group.
Question 5 of 5
A healthy man is in a region with high risk of catching malaria. What drug should be administered for individual chemoprophylaxis of malaria?
Correct Answer: A
Rationale: The correct answer is A: Chingamin (also known as Chloroquine). Chingamin is the drug of choice for chemoprophylaxis of malaria in regions with high risk. It is effective against Plasmodium falciparum, the most common malaria parasite. Chingamin is well-tolerated, affordable, and has a long track record of use. Sulfalen (Choice B) is not commonly used for malaria prophylaxis. Tetracycline (Choice C) is not recommended for malaria prophylaxis due to poor efficacy and resistance development. Metronidazole (Choice D) is not effective against malaria parasites.
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