A patient with diarrhea had stool microscopy revealing large, oval protozoa with a single nucleus and four flagella. What is the most likely causative agent?

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Question 1 of 5

A patient with diarrhea had stool microscopy revealing large, oval protozoa with a single nucleus and four flagella. What is the most likely causative agent?

Correct Answer: A

Rationale: Step 1: Large, oval protozoa with a single nucleus and four flagella indicate Giardia lamblia. Step 2: Giardia lamblia is a flagellated protozoan causing diarrhea. Step 3: It has a distinct appearance under microscopy. Step 4: Entamoeba histolytica causes dysentery with no flagella. Step 5: Balantidium coli is a ciliated protozoan with a larger size. Step 6: Trichomonas vaginalis lacks a cyst stage and causes genitourinary infections.

Question 2 of 5

Which bacteria produce a toxin that inhibits protein synthesis?

Correct Answer: A

Rationale: The correct answer is A: Shigella dysenteriae. This bacteria produces the Shiga toxin, which inhibits protein synthesis by interfering with the ribosomes. Shigella dysenteriae causes severe gastrointestinal illness. The other choices, B: Clostridium botulinum, produces a neurotoxin that blocks neurotransmitter release. C: Streptococcus pneumoniae causes pneumonia and other respiratory infections. D: Mycobacterium tuberculosis causes tuberculosis by infecting the lungs. Thus, based on the toxin production and mode of action, Shigella dysenteriae is the correct answer.

Question 3 of 5

A child with fever and swollen lymph nodes had a Gram-stained smear revealing Gram-negative rods with a safety pin appearance. What is the causative agent?

Correct Answer: A

Rationale: The correct answer is A: Yersinia pestis. This bacterium causes the plague, which presents with fever and swollen lymph nodes. The safety pin appearance on Gram stain is characteristic of Yersinia pestis. B: Francisella tularensis causes tularemia, which presents differently and does not show safety pin appearance on Gram stain. C: Brucella abortus causes brucellosis, which does not typically present with the same symptoms as described in the question. D: Clostridium botulinum causes botulism, which does not show safety pin appearance on Gram stain and does not typically present with fever and swollen lymph nodes.

Question 4 of 5

A stool sample from a patient with chronic diarrhea revealed cysts with four nuclei. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Entamoeba histolytica. This is because it is a protozoan parasite known to cause amoebic dysentery, presenting with chronic diarrhea and cysts with four nuclei in the stool sample. Giardia lamblia (B) causes giardiasis with trophozoites and cysts with two nuclei. Balantidium coli (C) is a ciliated parasite causing dysentery with large trophozoites. Trichomonas hominis (D) is a non-pathogenic flagellate often found in the human intestine. Thus, based on the specific characteristics of the cysts and clinical presentation, Entamoeba histolytica is the most likely causative agent.

Question 5 of 5

Which of the following bacteria produce a neurotoxin that affects the nervous system?

Correct Answer: C

Rationale: Rationale: Both Clostridium botulinum and Clostridium tetani produce neurotoxins. Botulinum toxin affects the nervous system by blocking neurotransmitter release, causing paralysis. Tetanus toxin affects the nervous system by interfering with neurotransmitter release, leading to muscle stiffness and spasms. Therefore, Choice C is correct. Choices A and B alone are incorrect because they only mention one of the bacteria that produces a neurotoxin. Choice D is incorrect because both bacteria mentioned in Choices A and B produce neurotoxins.

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