ATI RN
Microbiology A Systems Approach Test Bank Questions
Question 1 of 9
A patient with convulsive contractions of facial muscles was admitted to the infectious disease ward. From a scratch on his lower right extremity analysts isolated bacteria with terminal endospores that gave them drumstick appearance. What bacteria are compliant with given description?
Correct Answer: A
Rationale: Step-by-step rationale for the correct answer (A - Clostridium tetani): 1. The patient has convulsive contractions of facial muscles, indicating tetanus. 2. Isolation of bacteria with terminal endospores that have a drumstick appearance is characteristic of Clostridium tetani. 3. Clostridium tetani produces tetanospasmin toxin causing muscle spasms. 4. Therefore, the correct answer is Clostridium tetani (A). Summary of why other choices are incorrect: B: Clostridium botulinum causes botulism, not tetanus. C: Clostridium perfringens causes gas gangrene, not tetanus. D: Bacillus anthracis causes anthrax, not tetanus.
Question 2 of 9
The complex of all biological processes/mechanisms is responsible for the state of steady internal, physical, chemical conditions in the living systems and defense against all foreign agents is known as:
Correct Answer: C
Rationale: Rationale for Correct Answer (C - Immunity): 1. Immunity refers to the body's ability to defend against foreign agents. 2. Homeostasis is the state of steady internal conditions, not specifically related to defense. 3. Infection is the invasion and multiplication of pathogens, not the overall defense mechanism. 4. Commensalism is a symbiotic relationship where one organism benefits without harming the other.
Question 3 of 9
The specific prevention (by vaccination) of the disease gas gangrene (caused by Clostridium perfringens) is based on:
Correct Answer: B
Rationale: The correct answer is B: Anatoxin. An anatoxin is a toxin that has been rendered harmless while retaining its ability to stimulate an immune response. Gas gangrene is caused by the toxins produced by Clostridium perfringens, not the bacteria itself. Therefore, vaccination with an anatoxin can trigger the immune system to produce antibodies against the toxin, providing immunity against the disease. A: Killed whole cell vaccine - Gas gangrene is caused by toxins, not the whole bacterium. This type of vaccine may not be effective in preventing the disease. C: There is no specific prevention by vaccination - This is incorrect, as vaccination with an anatoxin can prevent gas gangrene. D: Alive attenuated vaccine - Attenuated vaccines contain live, weakened forms of the pathogen. However, for gas gangrene prevention, targeting the specific toxin with an anatoxin vaccine is more appropriate.
Question 4 of 9
A specimen stained by Ozheshko method contains rod-like microorganisms stained blue with round terminal components stained red. What are these components called?
Correct Answer: A
Rationale: The correct answer is A: Spores. In the Ozheshko staining method, spores appear blue with red terminal components. Spores are reproductive structures produced by some bacteria, fungi, and protozoa. Cilia are short, hair-like structures used for movement. Flagella are long, whip-like structures also used for movement. Capsules are outer protective layers surrounding some bacteria. In this case, the description of rod-like microorganisms with blue staining and red terminal components aligns with the characteristics of spores, making it the correct answer.
Question 5 of 9
Which of the following food media can be used for cultivation of Streptococcus pneumoniae:
Correct Answer: A
Rationale: The correct answer is A: Blood agar. Streptococcus pneumoniae is a fastidious bacterium that requires enriched media for growth. Blood agar provides the necessary nutrients and growth factors for the cultivation of S. pneumoniae, such as blood proteins and hemin. MacConkey agar (B) is selective for gram-negative bacteria and would not support the growth of S. pneumoniae. Peptone water (C) is a liquid medium that lacks the necessary nutrients for the growth of S. pneumoniae. Choice D is incorrect as blood agar is a suitable medium for cultivating S. pneumoniae.
Question 6 of 9
A patient in the oral surgery department has got purulent complication. Bacteriological analysis of the wound material found a culture that produces cyan pigment. What microorganism is the most probable causative agent?
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is known for producing a bluish-green pigment called pyocyanin, which presents as a cyan pigment. This bacterium is commonly associated with wound infections and is often found in oral surgery complications. Proteus vulgaris (B) and Klebsiella pneumoniae (D) are not typically associated with cyan pigment production, making them less likely causative agents. Bacillus subtilis (C) is not known to produce cyan pigment and is not a common pathogen in wound infections. Therefore, based on the presence of cyan pigment and the clinical context of an oral surgery complication, Pseudomonas aeruginosa is the most probable causative agent.
Question 7 of 9
Which of the following bacteria is known for causing the disease known as leprosy?
Correct Answer: A
Rationale: Step-by-step rationale: 1. Mycobacterium leprae is the correct answer as it is the bacteria known to cause leprosy. 2. Clostridium perfringens is incorrect as it is associated with gas gangrene. 3. Streptococcus pneumoniae is incorrect as it is commonly linked to pneumonia and meningitis. 4. Neisseria gonorrhoeae is incorrect as it causes gonorrhea, a sexually transmitted infection. In summary, Mycobacterium leprae is the only bacteria among the choices specifically known to cause leprosy, making it the correct answer.
Question 8 of 9
What is the primary purpose of a bacterial capsule?
Correct Answer: C
Rationale: The correct answer is C: Enhancing virulence by preventing phagocytosis. Bacterial capsules help bacteria evade the immune system by preventing phagocytosis, a process where immune cells engulf and destroy pathogens. This enhances the bacteria's virulence and ability to cause infections. Choices A, B, and D are incorrect because bacterial capsules do not directly contribute to protein synthesis, protect against desiccation, or facilitate motility.
Question 9 of 9
The role of pili in bacteria is:
Correct Answer: C
Rationale: The correct answer is C: adhesion to surfaces and conjugation. Pili are hair-like structures on the surface of bacteria that help them adhere to surfaces and facilitate the transfer of genetic material during conjugation. This is essential for bacterial survival and reproduction. Choice A is incorrect because protection from desiccation is typically associated with other structures like capsules. Choice B is incorrect as motility in bacteria is usually facilitated by flagella. Choice D is incorrect as spore formation involves the formation of specialized structures, not pili.