ATI RN
Chemotherapy drugs Questions
Question 1 of 5
A patient with AIDS has an extremely high viral RNA titer. While blood is being drawn from this patient, the syringe is accidentally dropped, contaminating the floor, which is made of porous material. The best way to deal with this is to
Correct Answer: D
Rationale: A 10% bleach solution is effective for decontaminating HIV on surfaces, as it inactivates the virus quickly and is practical for porous materials.
Question 2 of 5
Which one of the following enzymes is not unique to parasites?
Correct Answer: B
Rationale: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is present in both parasites and mammals, though its substrate specificity differs.
Question 3 of 5
This drug is the antimalarial agent most commonly associated with causing an acute hemolytic reaction in patients with glucose - 6 - phosphate dehydrogenase deficiency.
Correct Answer: D
Rationale: Primaquine causes hemolysis in G6PD-deficient patients due to oxidative stress on red blood cells.
Question 4 of 5
A missionary from Chicago is sent to work in a geographic region of a Cental American country wher onchocerca volvulus is endemic. Infections due to this tissue nematode (onchocerciasis) are a major cause of 'river blindness', since microfilariae migrate through subcutaneous tissues and concentrate in the eyes. Which one of the following durgs can be used prophylactically to prevent onchocerciasis?
Correct Answer: B
Rationale: Ivermectin is used prophylactically and therapeutically for onchocerciasis by killing microfilariae, preventing 'river blindness'.
Question 5 of 5
Which of the following agents used in drug combination regimens to treat testicular carcinoma is mot likely to cause nephrotoxicity?
Correct Answer: B
Rationale: Cisplatin is notorious for causing nephrotoxicity, a common side effect in testicular carcinoma treatment regimens.