A patient with a severe sore throat had a throat culture revealing Gram-positive cocci in chains. The bacteria were beta-hemolytic. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. This bacterium is the most likely causative agent due to its characteristic features. Streptococcus pyogenes is Gram-positive cocci in chains, which matches the description provided in the question. It is also known to be beta-hemolytic, causing complete lysis of red blood cells on blood agar. Streptococcus pyogenes is a common pathogen causing sore throat, often associated with pharyngitis. Explanation for incorrect choices: B: Streptococcus pneumoniae - This bacterium is Gram-positive but usually occurs in pairs (diplococci) and is alpha-hemolytic. C: Enterococcus faecalis - This bacterium is Gram-positive cocci but is not typically beta-hemolytic and is not commonly associated with sore throat infections. D: Staphylococcus aureus - This bacterium is Gram-positive cocci but usually occurs in clusters and

Correct Answer: B

Rationale: The correct answer is B: Anatoxin. An anatoxin is a toxin that has been rendered harmless while retaining its ability to stimulate an immune response. Gas gangrene is caused by the toxins produced by Clostridium perfringens, not the bacteria itself. Therefore, vaccination with an anatoxin can trigger the immune system to produce antibodies against the toxin, providing immunity against the disease. A: Killed whole cell vaccine - Gas gangrene is caused by toxins, not the whole bacterium. This type of vaccine may not be effective in preventing the disease. C: There is no specific prevention by vaccination - This is incorrect, as vaccination with an anatoxin can prevent gas gangrene. D: Alive attenuated vaccine - Attenuated vaccines contain live, weakened forms of the pathogen. However, for gas gangrene prevention, targeting the specific toxin with an anatoxin vaccine is more appropriate.

Correct Answer: C

Rationale: Rationale for Correct Answer (C - Immunity): 1. Immunity refers to the body's ability to defend against foreign agents. 2. Homeostasis is the state of steady internal conditions, not specifically related to defense. 3. Infection is the invasion and multiplication of pathogens, not the overall defense mechanism. 4. Commensalism is a symbiotic relationship where one organism benefits without harming the other.

Correct Answer: D

Rationale: Rationale: 1. Mycobacterium tuberculosis, Legionella pneumophila, Brucella melitensis can evade complete phagocytosis. 2. Mycobacterium tuberculosis inhibits phagosome-lysosome fusion. 3. Legionella pneumophila can prevent phagosome maturation. 4. Brucella melitensis can survive and replicate within phagocytes. 5. A + B + C together represent non-complete phagocytosis. Summary: - A, B, C individually cause incomplete phagocytosis. - Only when all three are present together (D) is non-complete phagocytosis observed.

Correct Answer: D

Rationale: The correct answer is D: Sporotrichosis. Sporotrichosis is caused by the fungus Sporothrix schenckii, which commonly presents as a subcutaneous infection. In the given case, the presence of a small abscess with yellowish-green pus containing white granules is indicative of sporotrichosis. The histological examination showing drusen of a fungus, plasmatic and xanthome cells, and macrophages further supports the diagnosis of sporotrichosis. Choice A: Actinomycosis is a bacterial infection caused by Actinomyces species, not a fungal infection. Choice B: Aspergillosis is caused by Aspergillus species and typically presents as a pulmonary infection, not a subcutaneous abscess as described in the case. Choice C: Candidosis is caused by Candida species and usually presents as mucocutaneous infections, not a subcutaneous abscess with the

Correct Answer: C

Rationale: The correct answer is C: Thick peptidoglycan layer. Gram-positive bacteria have a thick peptidoglycan layer in their cell wall, which retains the crystal violet stain during Gram staining. This thick layer is a key characteristic feature that helps differentiate Gram-positive bacteria from Gram-negative bacteria. Rationale: 1. Gram-positive bacteria retain the crystal violet stain due to their thick peptidoglycan layer. 2. This thick layer provides structural support and protection to the cell. 3. Gram-positive bacteria lack an outer membrane, which is a feature of Gram-negative bacteria (Choice A). 4. Thin peptidoglycan layer is a characteristic of Gram-negative bacteria, not Gram-positive (Choice B). 5. Presence of LPS (lipopolysaccharide) is a feature of Gram-negative bacteria, not Gram-positive (Choice D). In summary, the presence of a thick peptidoglycan layer is a characteristic feature of Gram-positive

Correct Answer: C

Rationale: The correct answer is C: Vibrio. Cholera is caused by Vibrio cholerae bacteria. These bacteria produce a toxin that causes severe diarrhea and dehydration. Escherichia (choice A) and Salmonella (choice B) are known for causing other types of gastrointestinal infections but not cholera. Acinetobacter (choice D) typically causes respiratory infections, not gastrointestinal illnesses like cholera. Therefore, the correct choice is Vibrio as it is specifically associated with cholera.

Correct Answer: D

Rationale: The correct answer is D because HIV can be transmitted from a mother to a child through multiple modes: during delivery through mixing of blood, during pregnancy through the placenta, and via breastmilk during lactation. Each mode presents a risk of transmission due to the presence of the virus in bodily fluids. Therefore, all of the above options are preferred modes of transmission for HIV from a mother to a child. Choices A, B, and C alone do not fully encompass all the possible routes of transmission, making them incorrect.

Correct Answer: A

Rationale: The correct answer is A: Dysenteric amoeba. This is because dysenteric amoebas can cause asymptomatic parasitosis, where a healthy person carries cysts that can infect others. Dysenteric amoebas are known to infect the intestines and can be transmitted through contaminated food or water. Choice B, Malarial plasmodium, causes malaria transmitted through mosquitoes. Choice C, Enteral trichomonad, causes diarrhea and is transmitted through contaminated water. Choice D, Dermatotropic leishmania, causes skin lesions and is transmitted through sandfly bites. These choices do not fit the scenario of asymptomatic parasitosis in public catering establishments.