ATI RN
ATI Pharmacology Practice A Questions
Question 1 of 5
A patient with a new prescription for a HMG-CoA (statin) drug is instructed to take the
Correct Answer: D
Rationale: The best response among the options provided is "This timeframe correlates better with the natural diurnal rhythm of cholesterol production." Statins work by inhibiting HMG-CoA reductase, an enzyme responsible for cholesterol production in the liver. Cholesterol synthesis follows a diurnal rhythm, with higher levels produced at night. Therefore, taking a statin medication in the evening aligns with the body's natural pattern of cholesterol synthesis, optimizing the drug's effectiveness. This explanation helps the patient understand the rationale behind the timing of taking the medication and promotes better adherence to the prescribed regimen.
Question 2 of 5
Phenytoin is an antiarrhythmic and anticonvulsant that has an unlabeled use for:
Correct Answer: C
Rationale: Phenytoin is primarily known as an antiarrhythmic and anticonvulsant medication. However, it also has an unlabeled or off-label use for the management of neuropathic pain. Neuropathic pain is a condition that arises from damage or dysfunction affecting the nerves and can be challenging to treat. Phenytoin's mechanism of action in the central nervous system makes it potentially effective for neuropathic pain conditions, even though it is not its primary indication. It can help alleviate nerve-related pain, such as that associated with conditions like diabetic neuropathy or post-herpetic neuralgia. It is important to note that using medications for off-label purposes should be done under the guidance of a healthcare professional familiar with the drug's properties and potential side effects.
Question 3 of 5
The nurse is aware that the following solutions are routinely used to flush an IV device before and after the administration of blood to a patient is:
Correct Answer: A
Rationale: 0.9 percent sodium chloride, also known as normal saline, is routinely used to flush an IV device before and after the administration of blood to a patient. Normal saline is isotonic, meaning it has a similar concentration of salt and water as the body's cells. This makes it compatible for use in various medical procedures, including flushing IV devices to ensure patency and prevent clotting. Other solutions like 5 percent dextrose in water, sterile water, and heparin sodium are not typically used for flushing IV devices before and after blood administration.
Question 4 of 5
When taking Nitroglycerine (transdermal), you should have how many hours nitrate free each day?
Correct Answer: D
Rationale: When using Nitroglycerine transdermal patches, it is recommended to have a nitrate-free period of at least 10-12 hours each day to prevent the development of tolerance to the medication. Continuous exposure to nitrates can lead to a decrease in efficacy over time. By having a nitrate-free interval each day, the body has a chance to "reset" and maintain the effectiveness of the medication for angina control. It is crucial to follow this dosing schedule as directed by a healthcare provider to ensure optimal benefits and reduce the risk of tolerance.
Question 5 of 5
What type of diuretic is furosemide?
Correct Answer: A
Rationale: Furosemide is a loop diuretic. Loop diuretics act on the thick ascending limb of the loop of Henle in the kidney to inhibit sodium and chloride reabsorption, leading to increased excretion of water and electrolytes such as potassium and calcium. Loop diuretics are potent and are often used to treat conditions like edema, heart failure, and hypertension. Furosemide is commonly utilized to manage conditions such as congestive heart failure, high blood pressure, and edema associated with certain medical conditions.