A patient with a history of moderate to severe headache pain associated with nausea and vomiting is diagnosed with migraines. Which medication would the NP prescribe initially?

Correct Answer: D

Rationale: The correct answer is D: Sumatriptan. Sumatriptan is a specific medication used for acute migraine treatment by targeting serotonin receptors to reduce inflammation and pain. It is the initial choice due to its efficacy in relieving migraine symptoms. Meperidine (A) and Butorphanol (B) are opioid analgesics with potential for abuse and not recommended for routine migraine treatment. Aspirin (C) is a non-specific pain reliever and may not provide adequate relief for migraines compared to specific migraine medications like Sumatriptan.

Correct Answer: B

Rationale: The correct answer is B: If TSH high. In primary hypothyroidism, the thyroid gland fails to produce enough thyroid hormones, leading to elevated TSH levels as the body tries to stimulate the thyroid to produce more hormones. A high TSH is indicative of the pituitary gland's response to low thyroid hormone levels. Choices A, C, and D do not align with the typical hormonal profile seen in primary hypothyroidism. A high TSH is the key marker for suspecting primary hypothyroidism.

Correct Answer: C

Rationale: The correct answer is C: Beta blockers reduce effects. Beta blockers can mask the symptoms of hypoglycemia caused by glyburide or glipizide, leading to delayed recognition and treatment. This interaction is important for patients with diabetes as it can increase the risk of severe hypoglycemia. A: NSAIDs do not have a significant impact on the effectiveness of glyburide or glipizide. B: Statins do not interfere with the action of these medications. D: ACE inhibitors do not reduce the effects of glyburide or glipizide. In summary, beta blockers are a crucial consideration when taking glyburide or glipizide due to their potential to mask hypoglycemic symptoms, while NSAIDs, statins, and ACE inhibitors do not significantly affect the effectiveness of these medications.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: The correct answer is C, Topically. Percutaneous route involves applying the medication on the skin surface for absorption. Intramuscular (A) and subcutaneous (B) routes involve injections into muscle or tissue. Rectal route (D) involves inserting medication into the rectum. Topical route is the only option that aligns with percutaneous administration.