ATI RN
ATI Pharmacology Practice B Questions
Question 1 of 5
A patient who is taking amitriptyline (Elavil) reports constipation and dry mouth. The patient notes that these
Correct Answer: B
Rationale: The common side effects of amitriptyline (Elavil) include constipation and dry mouth. Increasing fluid intake can help alleviate these symptoms. Adequate hydration can aid in promoting bowel regularity and relieving dry mouth. It is important for the nurse to give the patient instructions to increase their fluid intake to manage these side effects rather than immediately discontinuing the medication or requesting a change in antidepressants. If the constipation and dry mouth persist or worsen despite increasing fluid intake, then the provider may need to be notified for further evaluation and management.
Question 2 of 5
This drug when taken orally reverses the hepatic necrosis effect of paracetamol :
Correct Answer: D
Rationale: Acetylcysteine is the antidote for acetaminophen (paracetamol) overdose. Acetaminophen overdose can lead to hepatic necrosis, and acetylcysteine is effective in preventing or reversing this hepatotoxicity. It works by replenishing depleted hepatic stores of glutathione, which is essential for detoxifying the reactive metabolite of acetaminophen. This helps to protect the liver cells from damage caused by the toxic metabolite of acetaminophen. Naloxone, vitamin K, warfarin, and diphenhydramine are not effective in reversing the hepatic necrosis caused by paracetamol overdose.
Question 3 of 5
The nurse administers IV ceftriaxone (Rocephin) to a client with pneumonia. Which precaution should the nurse take?
Correct Answer: C
Rationale: Ceftriaxone, a cephalosporin, treats pneumonia but risks hypersensitivity (e.g., rash, anaphylaxis). Monitoring for allergic reactions ensures safety, a key precaution. Dilution is standard but not the focus'protocol varies. Rapid infusion is too fast'30 minutes is typical. Undiluted risks irritation. Allergy monitoring aligns with cephalosporin's profile, critical in pneumonia where rapid intervention saves lives, making C the priority precaution.
Question 4 of 5
A severely immunocompromised female patient requires a blood transfusion. To prevent GVHD, the physician will order:
Correct Answer: C
Rationale: In order to prevent graft-versus-host disease (GVHD) in a severely immunocompromised patient receiving a blood transfusion, the physician will order irradiation of the donor blood. GVHD is a rare but serious complication that can occur when the donor's T lymphocytes attack the recipient's tissues. Irradiation of the blood eliminates the T lymphocytes, thereby reducing the risk of GVHD in immunocompromised patients. Diphenhydramine hydrochloride (Benadryl) and acetaminophen (Tylenol) are commonly used to manage transfusion reactions but do not specifically prevent GVHD. Administering the transfusion slowly over several hours does not directly address the risk of GVHD.
Question 5 of 5
The drug that will most likely be used for treatment of erectile dysfunction (ED) is
Correct Answer: D
Rationale: Sildenafil (Viagra), a phosphodiesterase-5 inhibitor, enhances penile blood flow by increasing cyclic GMP, directly treating erectile dysfunction (ED) and is the standard first-line therapy. Leuprolide, a GnRH agonist, suppresses testosterone for prostate cancer, potentially worsening ED. Finasteride, for benign prostatic hyperplasia (BPH), reduces prostate size but may cause ED as a side effect, not treat it. Tamsulosin, an alpha-blocker for BPH, improves urinary flow but isn't indicated for ED and can lower blood pressure. Sildenafil's targeted action on vascular mechanisms in ED distinguishes it, offering rapid efficacy and a well-established safety profile for this condition.