A patient was treated with digoxin and he develop signs and symptoms of * digoxin toxicity caused by furosemide therapy. What did the diuretic most likely do to precipitate the digoxin toxicityy?

Correct Answer: C

Rationale: The correct answer is C: caused by hypokalemia. Furosemide, a loop diuretic, can lead to potassium loss (hypokalemia), which can exacerbate digoxin toxicity. Low potassium levels increase the risk of digoxin binding more strongly to cardiac tissue, leading to toxicity symptoms. Hypocalcemia (A) and hyponatremia (B) are not directly related to digoxin toxicity, making them incorrect choices. Choice D is incorrect as hypokalemia is a known risk factor for digoxin toxicity.

Correct Answer: B

Rationale: Rationale: Mannitol is typically used for cerebral edema due to its osmotic diuretic properties that reduce intracranial pressure. Furosemide is a loop diuretic commonly used for conditions like pulmonary edema. Therefore, intravenous furosemide is an alternative potent diuretic to Mannitol in the treatment of cerebral edema. Summary: A: Cardiac edema - Loop diuretics like furosemide are commonly used in cardiac edema, not Mannitol. C: Cirrhotic edema - Loop diuretics are used in cirrhotic edema, but Mannitol is not typically indicated. D: Pulmonary edema - Furosemide is commonly used in pulmonary edema, but Mannitol is not indicated for this condition.

Correct Answer: B

Rationale: Desmopressin reduces urine volume in diabetes insipidus by mimicking the action of vasopressin, which is deficient in this condition. It helps to increase water reabsorption in the kidneys, leading to decreased urine output. Central and nephrogenic diabetes insipidus are not directly treated with desmopressin as they involve different underlying mechanisms. Therefore, choice B is the correct answer.

Correct Answer: B

Rationale: The correct answer is B: Protein. In the urine, the presence of protein can indicate kidney damage or malfunction. Normally, the kidneys filter out waste products, toxins, and excess substances, but proteins are too large to pass through healthy kidney filters. If protein is found in the urine, it suggests a problem with the kidney's filtration system. This can be a sign of conditions like kidney disease or diabetes. Rationale for why the other choices are incorrect: A: Urinary bladder and urethra are not typically associated with the presence of substances like protein in urine. C: Glucose in the urine may indicate diabetes or other health issues, but it is not the most common substance to be tested for in routine urinalysis. D: Kidney dialysis is a treatment for kidney failure, not a substance present in urine.

Correct Answer: C

Rationale: The correct answer is C: Hypophosphatemia. In end-stage renal failure (ESRF) patients, hypophosphatemia is not a common finding due to impaired renal excretion of phosphate. Metastatic calcification (A) occurs due to high calcium-phosphate product, peripheral neuropathy (B) can result from uremic toxins, and hyperparathyroidism (D) is common in ESRF due to secondary hyperparathyroidism. Therefore, hypophosphatemia is the least likely finding in ESRF patients.