A patient underwent esophagogastroduodenoscopy. Analysis of the biopsy material enabled doctors to diagnose him with helicobacteriosis. What property of the bacteria found in this patient had to be obligatory taken into account during their cultivation?

Correct Answer: A

Rationale: Step-by-step rationale for why choice A is correct: 1. Helicobacter pylori, the bacteria causing helicobacteriosis, is microaerophilic, requiring low oxygen levels. 2. Cultivation conditions must mimic the natural environment of the bacteria. 3. Failure to provide a microaerophilic environment can hinder bacterial growth. 4. Thus, the ability to cultivate these bacteria requires consideration of their microaerophilic nature. Summary: - Choice A is correct because Helicobacter pylori is a microaerophilic bacteria. - Choice B (Presence of urease) is incorrect as it is a characteristic used for diagnosis, not cultivation. - Choice C (Absence of spores and capsules) is incorrect as it does not relate to cultivation requirements. - Choice D (Colonization of gastral cells) is incorrect as it pertains to bacterial behavior, not cultivation needs.

Correct Answer: C

Rationale: The correct answer is C: S.aureus. Stomatitis is commonly caused by S.aureus due to its ability to form clusters of oval polymorphous Gram-positive microorganisms. S.aureus is known to colonize the oral mucous membrane and can cause infections, especially after prolonged antibiotic use. Explanation for other choices: A: С.albicans - Candida albicans is a fungus commonly associated with oral thrush, not typically causing stomatitis. B: C.perfringens - Clostridium perfringens is a bacterium associated with food poisoning and gas gangrene, not commonly causing stomatitis. D: S.pyogenes - Streptococcus pyogenes is known to cause strep throat and skin infections, but not typically associated with stomatitis.

Correct Answer: A

Rationale: The correct answer is A: Nucleoid. The bacterial genome is located in the nucleoid, a region within the bacterial cell where the genetic material is condensed and organized. This structure is not the same as a nucleus found in eukaryotic cells. The other choices (B: Nucleotide and C: ATP) are incorrect because nucleotide refers to a building block of DNA or RNA, and ATP is a molecule used for energy transfer in cells, neither of which specifically houses the bacterial genome. Choice D: None of the above is incorrect as well, as the correct term for the compact structure containing the bacterial genome is the nucleoid.

Correct Answer: D

Rationale: The thin microorganisms described with 12-14 equal ringlets and pale-pink sharp points are characteristic of Borrelia spirochetes, the causative agent of relapsing fever. The ringlet appearance corresponds to the characteristic coiled structure of Borrelia spirochetes. The length of 10-13 mkm falls within the typical size range of Borrelia spirochetes. This pathogen is commonly identified in Romanovsky-Giemsa stained samples from patients with relapsing fever. Summary of other choices: A: Leishmaniasis - Leishmania parasites are larger and do not have the described ringlets or pale-pink sharp points. B: Leptospirosis - Leptospira bacteria are not described as having ringlets or pale-pink sharp points. C: Surra - Surra is caused by Trypanosoma evansi, and the description does not match the characteristics of this parasite.

Correct Answer: C

Rationale: The correct answer is C: plasmids. Plasmids are nonchromosomal DNA molecules commonly found in bacterial cells, providing additional genetic material for bacteria. They are not essential for bacterial survival but can confer advantages such as antibiotic resistance. Endospores (A) are dormant bacterial structures resistant to harsh conditions. Transposons (B) are mobile genetic elements that can move within a genome. Prions (D) are misfolded proteins causing neurodegenerative diseases, not DNA molecules.

Correct Answer: A

Rationale: The correct answer is A: Mononuclears, T-lymphocytes and lymphokines. In a Mantoux test reaction, mononuclear cells, mainly T-lymphocytes, are activated by the injected allergen. These T-lymphocytes release lymphokines, leading to the observed swelling, hyperaemia, and tenderness. Granulocytes and IgG (choice B) are not the primary players in this type of delayed hypersensitivity reaction. Plasmatic cells (choice C) are not involved in the initial stages of this reaction. B-lymphocytes and IgM (choice D) are not the key components in the Mantoux test reaction.

Correct Answer: B

Rationale: The correct answer is B: Shigellosis. Shigellosis is caused by the bacteria Shigella, commonly transmitted through contaminated food and water. The bacteria can spread easily in unsanitary conditions. Mumps (A) is a viral infection spread through respiratory droplets. Legionellosis (C) is caused by the Legionella bacteria found in water sources like cooling towers. Tuberculosis (D) is a bacterial infection transmitted through the air. Therefore, the correct answer is B as it directly relates to contaminated food transmission.

Correct Answer: A

Rationale: Step-by-step rationale for why choice A is correct: 1. Helicobacter pylori, the bacteria causing helicobacteriosis, is microaerophilic, requiring low oxygen levels. 2. Cultivation conditions must mimic the natural environment of the bacteria. 3. Failure to provide a microaerophilic environment can hinder bacterial growth. 4. Thus, the ability to cultivate these bacteria requires consideration of their microaerophilic nature. Summary: - Choice A is correct because Helicobacter pylori is a microaerophilic bacteria. - Choice B (Presence of urease) is incorrect as it is a characteristic used for diagnosis, not cultivation. - Choice C (Absence of spores and capsules) is incorrect as it does not relate to cultivation requirements. - Choice D (Colonization of gastral cells) is incorrect as it pertains to bacterial behavior, not cultivation needs.

Correct Answer: A

Rationale: Cell-mediated immunity plays a crucial role in combating infections with intracellular pathogens by activating T cells to directly kill infected cells. Facultative and obligate intracellular pathogens, such as viruses and some bacteria, require cell-mediated immunity for effective clearance. Option A is correct due to the specificity of this immune response. Choices B, C, and D are incorrect as they are primarily associated with humoral immunity involving antibodies and not T cell responses against intracellular pathogens.