ATI RN
ATI Pharmacology Book Questions
Question 1 of 5
A patient taking sunitinib reports that the skin on the hands and feet is red, painful, and has some blisters. Which action is appropriate for the nurse to take?
Correct Answer: D
Rationale: Sunitinib, a multikinase inhibitor, can cause hand-foot syndrome, a condition characterized by redness, pain, and blistering on the palms and soles. This side effect can be severe and may require dose adjustments or treatment interruptions. The nurse should notify the oncologist to evaluate the severity of the symptoms and determine if a dosage reduction is necessary. While protective measures like wearing gloves can help, they are not sufficient if the symptoms are severe. Documentation alone is inadequate for managing this potentially debilitating side effect.
Question 2 of 5
A 30-year-old male patient who is treated with haloperidol for his diagnosis of schizophrenia is considered to be well-managed symptomatically for his psychotic symptoms. However, he is reporting restlessness, the inability to sit still at the dinner table, and his family notices that he is pacing up and down the hallway frequently. Of the following, which is the best medication to treat this antipsychotic-induced akathisia?
Correct Answer: E
Rationale: Haloperidol's D2 blockade causes akathisia—restlessness and pacing—as an EPS. Propranolol, a beta-blocker, reduces akathisia by modulating catecholamine activity, a first-line treatment per guidelines, unlike anticholinergics (benztropine) which target dystonia/parkinsonism. Dantrolene treats muscle spasticity, not akathisia. Amoxapine, an antidepressant, worsens psychosis. Bromocriptine, a dopamine agonist, risks psychosis exacerbation. Propranolol's efficacy, safety, and specificity for akathisia make it the best choice, replacing D as instructed.
Question 3 of 5
The nurse teaches the client about the difference between oral and nasal decongestants. The nurse evaluates that learning has been effective when the client makes which statement?
Correct Answer: A
Rationale: Oral decongestants (e.g., pseudoephedrine) act systemically, raising blood pressure via vasoconstriction, a key difference from nasal decongestants (e.g., oxymetazoline), which act locally but risk rebound congestion. The statement 'Oral decongestants can cause hypertension' shows the client grasps this systemic effect, indicating effective teaching. Nasal decongestants aren't safe for a month ; they cause rebound after 3-5 days. Only nasal decongestants typically cause rebound , not oral. Oral efficacy varies, not inherently superior. Choice A reflects accurate understanding of oral decongestants' broader impact, critical for safe use, making it the best learning indicator.
Question 4 of 5
The plasma clearance of a drug:
Correct Answer: A
Rationale: Plasma clearance reflects the volume of plasma cleared of the drug per unit time, combining renal and hepatic elimination pathways.
Question 5 of 5
When collecting a medication history from a patient with primary open-angle glaucoma, the nurse identifies several drugs that could exacerbate glaucoma. Which drug poses a priority concern for this particular patient?
Correct Answer: B
Rationale: Oxymetazoline, a decongestant, can exacerbate glaucoma by causing vasoconstriction and increasing intraocular pressure. Cyclobenzaprine (A) is not typically associated with worsening glaucoma. The nurse should prioritize identifying and addressing the use of oxymetazoline in this patient.