A patient taking SMZ/TMP asks the nurse what the name means. The nurse replies sulfamethoxazole is combined with trimethoprim in SMZ/TMP to help the drug effectiveness. How does this work?

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ATI Intro to Pharmacology Quizlet Questions

Question 1 of 5

A patient taking SMZ/TMP asks the nurse what the name means. The nurse replies sulfamethoxazole is combined with trimethoprim in SMZ/TMP to help the drug effectiveness. How does this work?

Correct Answer: D

Rationale: SMZ/TMP (sulfamethoxazole/trimethoprim) works synergistically to inhibit bacterial folate synthesis at two different steps, making it effective against a broad spectrum of gram-positive and gram-negative organisms. It does not act as an anesthetic (A), displace trimethoprim (B), or increase excretion in the bladder (C). The combination enhances antibacterial activity and reduces the risk of resistance.

Question 2 of 5

The physician has prescribed sertraline (Zoloft) for the patient who is anxious and depressed. The patient calls the nurse to report that he has experienced delayed ejaculation since being on this medication. What is the best response by the nurse?

Correct Answer: B

Rationale: Sertraline, an SSRI, often causes sexual side effects like delayed ejaculation-common, per patient data-but depression treatment outweighs this for now. Switching is an option, not immediate. Suicide risk from stopping is possible but not assumed. It rarely resolves alone-management varies. Prioritizing depression balances care, per guidelines.

Question 3 of 5

When administering the anticoagulant drug Warfarin, what is one of the two lab tests you should monitor to distinguish the effectiveness of the drug?

Correct Answer: B

Rationale: When administering the anticoagulant drug Warfarin, one of the two lab tests you should monitor to distinguish the effectiveness of the drug is the International Normalized Ratio (INR). INR measures the time it takes for blood to clot and is used to monitor the effects of Warfarin therapy. The target INR range for patients on Warfarin therapy varies depending on the indication for treatment, but in general, a higher INR indicates that the blood is taking longer to clot, which means the Warfarin is working effectively to prevent blood clots. Regular monitoring of the INR levels is essential to ensure that patients are receiving an appropriate dose of Warfarin to prevent both clotting and bleeding complications.

Question 4 of 5

A patient with diabetes has a new prescription for the ACE inhibitor lisinopril. She questions this order because her physician has never told her that she has hypertension. What is the best explanation for this order?

Correct Answer: D

Rationale: The correct explanation for the prescription of the ACE inhibitor lisinopril for a patient with diabetes who does not have hypertension is that this medication has cardioprotective properties. ACE inhibitors, such as lisinopril, have been shown to have beneficial effects beyond just lowering blood pressure. They have been found to reduce the risk of cardiovascular events and complications in patients with diabetes, even in the absence of hypertension. Therefore, the prescription of lisinopril for a patient with diabetes may be for its cardioprotective properties rather than for hypertension control.

Question 5 of 5

A patient arrives in the emergency department with severe chest pain. The patient reports that the pain has been occurring off and on for a week now. Which assessment finding would indicate the need for cautious use of nitrates and nitrites?

Correct Answer: A

Rationale: A patient arriving in the emergency department with severe chest pain and a history of episodic chest pain over the past week may be experiencing a myocardial infarction or other serious cardiac event. Nitrates and nitrites are commonly used to manage chest pain in such situations because they help dilate blood vessels, improve blood flow to the heart, and reduce the workload on the heart.

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