ATI RN
ATI Intro to Pharmacology Quizlet Questions
Question 1 of 5
A patient taking SMZ/TMP asks the nurse what the name means. The nurse replies sulfamethoxazole is combined with trimethoprim in SMZ/TMP to help the drug effectiveness. How does this work?
Correct Answer: D
Rationale: SMZ/TMP (sulfamethoxazole/trimethoprim) works synergistically to inhibit bacterial folate synthesis at two different steps, making it effective against a broad spectrum of gram-positive and gram-negative organisms. It does not act as an anesthetic (A), displace trimethoprim (B), or increase excretion in the bladder (C). The combination enhances antibacterial activity and reduces the risk of resistance.
Question 2 of 5
Biperiden hydrochloride (Akineton) is added to a list of antiparkinsonian medications that an elderly client is taking. Which of the following instructions made by the nurse that needs further learning?
Correct Answer: C
Rationale: Walking in the morning for direct sunlight is unrelated to the use of biperiden hydrochloride (Akineton) and does not address its side effects or therapeutic effects. Avoiding alcohol and caffeine, managing dry mouth, and increasing fiber and fluid intake are appropriate instructions. Therefore, the statement about sunlight indicates a need for further learning.
Question 3 of 5
A history of which of the following is a contraindication to short-term HRT to prevent menopausal vasomotor symptoms and menopausal vaginitis?
Correct Answer: B
Rationale: Short-term HRT (estrogen ± progestin) relieves menopausal symptoms. Depression isn't a contraindication; HRT may improve mood. Breast cancer is a absolute contraindication due to estrogen's proliferative risk, outweighing benefits. Hysterectomy allows estrogen-only HRT, bronchitis and eczema are unrelated. Breast cancer's link to estrogen drives this restriction, critical for safe hormone use.
Question 4 of 5
Clearance:
Correct Answer: A
Rationale: Clearance (CL = rate of elimination / plasma concentration) is the amount of drug removed per unit time relative to concentration, a true statement defining its calculation. It's constant for first-order kinetics drugs at therapeutic levels, true. Lithium's clearance is moderate, not very high, handled by kidneys, so that's false. Phenytoin's clearance decreases with concentration (zero-order at high doses), not independent, making that false. Clearance isn't inversely proportional to Vd but related via half-life. This definition is essential for dosing regimens, ensuring steady-state maintenance.
Question 5 of 5
The student nurse has completed an initial pharmacology course and tells the nursing instructor that it was difficult and she is glad it is over. What is the best response by the nursing instructor?
Correct Answer: B
Rationale: Pharmacology's complexity means learning is ongoing-new drugs, research, and applications evolve, preventing full mastery and requiring continuous growth. Applying knowledge is true but assumes completion. Painful learning dismisses positivity. Graduate courses are premature. Gradual learning reflects the field's dynamic nature, preparing the student for lifelong education, a realistic and encouraging perspective.