A patient taking SMZ/TMP asks the nurse what the name means. The nurse replies sulfamethoxazole is combined with trimethoprim in SMZ/TMP to help the drug effectiveness. How does this work?

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Question 1 of 5

A patient taking SMZ/TMP asks the nurse what the name means. The nurse replies sulfamethoxazole is combined with trimethoprim in SMZ/TMP to help the drug effectiveness. How does this work?

Correct Answer: D

Rationale: SMZ/TMP (sulfamethoxazole/trimethoprim) is a combination antibiotic where the two drugs work synergistically to inhibit sequential steps in bacterial folate synthesis, enhancing antibacterial efficacy against a wide range of gram-positive and gram-negative organisms. Choice D correctly identifies this synergistic effect. Choice A is incorrect as neither drug is an anesthetic. Choice B is pharmacologically inaccurate, and Choice C misrepresents their mechanism, as they target bacterial metabolism, not excretion.

Question 2 of 5

A physician has ordered peak and trough levels of a medication. When would the nurse schedule the trough level specimen?

Correct Answer: C

Rationale: The trough level, which measures the lowest drug concentration, is typically drawn 30 minutes before the next dose to assess the drug's baseline before administration.

Question 3 of 5

A hospitalized patient asks the nurse for some aspirin for my headache. There is no order for aspirin for this patient. What will the nurse do?

Correct Answer: D

Rationale: Nurses cannot administer medications without a physician's order due to legal and safety standards; they must consult the doctor.

Question 4 of 5

What would a nurse instruct a patient to do after administration of a sublingual medication?

Correct Answer: B

Rationale: Sublingual medications must dissolve under the tongue without swallowing to ensure absorption through the oral mucosa.

Question 5 of 5

A nurse flushes an intravenous lock before and after administering a medication. What is the rationale for this step?

Correct Answer: C

Rationale: Flushing an IV lock clears residual medication and prevents clotting, maintaining patency of the line.

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