A patient suffers from severe postoperative pseudomonadous infection. What of the following antibiotics should be administered in this case?

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ATI RN Test Bank

Microbiology Basic and Clinical Principles Test Bank Questions

Question 1 of 9

A patient suffers from severe postoperative pseudomonadous infection. What of the following antibiotics should be administered in this case?

Correct Answer: A

Rationale: The correct answer is A: Amikacin sulfate. Pseudomonas aeruginosa is commonly resistant to many antibiotics, but aminoglycosides like Amikacin have good activity against it. Step 1: Identify the pathogen causing the infection. Step 2: Consider the antibiotic's spectrum of activity against the pathogen. Step 3: Choose an antibiotic with proven efficacy. Amikacin is a good choice due to its effectiveness against Pseudomonas. Choice B, Benzylpenicillin, is a penicillin which is not effective against Pseudomonas. Choice C, Cephazolin, is a cephalosporin with limited activity against Pseudomonas. Choice D, Erythromycin, is a macrolide which is not effective against Pseudomonas.

Question 2 of 9

A 45 year old male died from disseminated tuberculosis. On autopsy the symptoms of tuberculosis were confirmed by both microscopical and histological analyses. What kind of hypersensitivity reaction underlies the process of granuloma development?

Correct Answer: A

Rationale: The correct answer is A: Delayed hypersensitivity reaction. In granuloma development in tuberculosis, macrophages present antigen to T cells, leading to a delayed hypersensitivity reaction. This triggers the recruitment of more macrophages and formation of granulomas. Antibody-dependent cytotoxicity (B) and complement-dependent cytotoxicity (C) involve antibodies and complement proteins in immediate hypersensitivity reactions, which are not the primary mechanisms in tuberculosis. Anaphylactic reaction (D) is an acute systemic allergic reaction mediated by IgE antibodies, not relevant to granuloma formation in tuberculosis.

Question 3 of 9

A sputum smear from a patient with pneumonia revealed Gram-positive cocci in pairs with pointed ends and capsules. What is the likely microorganism?

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pneumoniae. The description of Gram-positive cocci in pairs with pointed ends and capsules matches the morphology of S. pneumoniae. This bacterium is known to cause pneumonia, especially in individuals with underlying conditions like COPD. Staphylococcus aureus (B) typically appears in clusters, not pairs. Klebsiella pneumoniae (C) is a Gram-negative rod, not a cocci. Neisseria meningitidis (D) is a Gram-negative diplococcus, not a cocci. Hence, based on the morphology and clinical context, Streptococcus pneumoniae is the likely microorganism causing pneumonia in this patient.

Question 4 of 9

Dengue virus is member of a family called

Correct Answer: C

Rationale: The correct answer is C: Flaviviridae. Dengue virus belongs to the Flaviviridae family because it is a flavivirus. Flaviviruses are a group of RNA viruses known to cause diseases in humans, such as dengue fever, Zika virus, and yellow fever. This family is characterized by its single-stranded, positive-sense RNA genome and enveloped virion structure. Hepadnaviridae (choice A), Parvoviridae (choice B), and Picornaviridae (choice D) are all different families of viruses that do not include the dengue virus. Hepadnaviridae includes hepatitis B virus, Parvoviridae includes parvoviruses, and Picornaviridae includes enteroviruses like poliovirus.

Question 5 of 9

A 25-year-old patient reports pain, burning at urination and scarce secretion in the morning. Urine samples are taken and cultivated on blood and MacConkey agar. After 24 hours of incubation, the culture are sterile. Which one of the following bacteria is the most probable cause of this disease?

Correct Answer: B

Rationale: The correct answer is B: Chlamydia trachomatis. This is because Chlamydia trachomatis is an obligate intracellular bacterium that cannot be cultured on standard agar plates. The symptoms described by the patient, such as pain, burning at urination, and scarce secretion in the morning, are indicative of a possible chlamydial infection. Additionally, the fact that the urine cultures are sterile after 24 hours of incubation suggests that the causative agent is not a typical bacteria like Escherichia coli, Streptococcus pneumoniae, or Neisseria gonorrhoeae, which would normally grow on agar plates. Therefore, Chlamydia trachomatis is the most probable cause of this disease. Summary: A: Escherichia coli - Incorrect, as it is a common cause of urinary tract infections and would typically grow on agar plates. C: Streptococcus pneumoniae - Incorrect, as it is

Question 6 of 9

Growth of bacteria is a result of:

Correct Answer: B

Rationale: The growth of bacteria is a result of water adsorption because water is essential for various metabolic processes within the bacterial cells, such as nutrient uptake, energy production, and waste removal. Water serves as a medium for chemical reactions to occur and provides structural support to the bacteria. Without sufficient water, bacteria cannot thrive and reproduce. A: Air consumption is incorrect because while bacteria may require oxygen for respiration, it is not the primary factor for their growth. C: Enzyme production is incorrect because enzymes are important for various cellular functions but do not directly influence bacterial growth. D: Radio isotopes are incorrect as they are not essential for bacterial growth and can even be harmful to bacterial cells.

Question 7 of 9

A 12-year-old boy presents with nausea, frequent repeated vomiting that first occurred after eating canned vegetables. Objectively: the patient has dry mucous membranes, muscular hypotonia, anisocoria, mydriasis, dysphagia and dysarthria. What is the most likely diagnosis?

Correct Answer: A

Rationale: The most likely diagnosis is A: Botulism. The symptoms, such as nausea, vomiting after eating canned vegetables, dry mucous membranes, muscular hypotonia, anisocoria, mydriasis, dysphagia, and dysarthria, are classic signs of botulism poisoning. Botulism is caused by the neurotoxin produced by Clostridium botulinum bacteria found in improperly canned or preserved food. The neurotoxin affects the nervous system, leading to symptoms like those described. Shigellosis (B), Salmonellosis (C), and Cholera (D) typically present with different symptoms such as diarrhea, fever, and abdominal pain, which are not seen in this patient.

Question 8 of 9

Which type of bacteria are capable of surviving in high salt concentrations?

Correct Answer: C

Rationale: Correct Answer: C: Halophiles Rationale: 1. Halophiles are bacteria adapted to high salt environments. 2. They have specific mechanisms to tolerate high salt concentrations. 3. Acidophiles thrive in acidic conditions. 4. Thermophiles prefer high temperature environments. 5. Mesophiles grow best at moderate temperatures.

Question 9 of 9

A patient with a sore throat and fever had a throat culture revealing Gram-positive cocci in chains. The bacteria were beta-hemolytic. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. 1. Gram-positive cocci in chains suggest streptococci. 2. Beta-hemolytic activity indicates Streptococcus pyogenes. 3. Streptococcus pyogenes is commonly associated with sore throat (pharyngitis) and fever. 4. Streptococcus pneumoniae (choice B) is alpha-hemolytic and mainly causes pneumonia. 5. Enterococcus faecalis (choice C) is not typically associated with sore throat. 6. Staphylococcus aureus (choice D) is not commonly beta-hemolytic and is not a typical cause of pharyngitis.

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