A patient suffering from syphilis was prescribed a drug the action of which based upon disturbed generation of murein leading to death of the causative agent. What drug is it?

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Microbiology An Introduction 13th Edition Test Bank Questions

Question 1 of 5

A patient suffering from syphilis was prescribed a drug the action of which based upon disturbed generation of murein leading to death of the causative agent. What drug is it?

Correct Answer: A

Rationale: The correct answer is A: Benzylpenicillin sodium salt. Benzylpenicillin is a beta-lactam antibiotic that inhibits the synthesis of bacterial cell walls by disrupting the formation of murein (peptidoglycan), leading to bacterial cell death. This mechanism specifically targets the causative agent of syphilis, Treponema pallidum. - Choice B: Bijochinol is not a known drug used to treat syphilis. - Choice C: Ciprofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA replication and is not the first-line treatment for syphilis. - Choice D: Azithromycin is a macrolide antibiotic that interferes with bacterial protein synthesis and is commonly used to treat other infections but is not the preferred treatment for syphilis.

Question 2 of 5

A businessman came to India from South America. On examination the physician found that the patient was suffering from sleeping-sickness. What was the way of invasion?

Correct Answer: B

Rationale: The correct answer is B: As a result of mosquito's bites. Sleeping sickness, also known as African trypanosomiasis, is caused by the parasite Trypanosoma transmitted by tsetse flies, not mosquitoes. Tsetse flies are primarily found in Africa, not South America. Choice A is incorrect as bug bites do not transmit sleeping sickness. Choice C is incorrect as contaminated fruits and vegetables do not transmit the disease. Choice D is incorrect as dirty hands do not play a role in the transmission of sleeping sickness.

Question 3 of 5

What drug should be administered for individual prevention of malaria?

Correct Answer: A

Rationale: The correct answer is A: Chingamin. Chingamin is a type of antimalarial drug that is commonly used for individual prevention of malaria. It works by targeting the malaria parasite in the body, preventing its growth and spread. Rifampicin (B), Ampicillin (C), and Gentamicin (D) are not effective for preventing malaria as they are antibiotics that target bacterial infections, not parasitic infections like malaria. Therefore, Chingamin is the most appropriate choice for individual prevention of malaria due to its specific antimalarial properties.

Question 4 of 5

A sick man with high temperature and a lot of tiny wounds on the body has been admitted to the hospital. Lice have been found in the folds of his clothing. What disease can be suspected in the patient?

Correct Answer: A

Rationale: The correct answer is A: Epidemic typhus. This disease is caused by the bacterium Rickettsia prowazekii, which is transmitted by body lice. The symptoms include high fever, body rash, and tiny wounds due to scratching. The presence of lice in the clothing suggests a possible lice-borne disease like epidemic typhus. Summary: - B: Tularemia is caused by the bacterium Francisella tularensis, transmitted through ticks, deer flies, and contact with infected animals. Lice are not involved in its transmission. - C: Scabies is a skin infestation caused by the mite Sarcoptes scabiei, leading to itching and skin rashes. It is not associated with high fever or lice infestation. - D: Malaria is caused by Plasmodium parasites, transmitted by infected mosquitoes. The symptoms differ from those described in the scenario, and lice are not involved in its

Question 5 of 5

A sample of a finished dosage form was found to be contaminated with some microorganisms exhibiting the following properties: greenish fluorescent colonies of gram-negative nonsporeforming bacilli that grew on the medium for the detection of pyocyanin. The bacilli release the bluegreen pigment into the medium. What microorganisms contaminated the finished dosage form?

Correct Answer: A

Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is a gram-negative bacilli that produce pyocyanin, a blue-green pigment. The presence of greenish fluorescent colonies of gram-negative nonsporeforming bacilli that release blue-green pigment matches the characteristics of Pseudomonas aeruginosa. Now, let's analyze the other choices: B: Enterobacteriaceae - While some Enterobacteriaceae can be gram-negative bacilli, they do not typically produce pyocyanin or exhibit the specific characteristics described in the question. C: Staphylococcus aureus - Staphylococcus aureus is a gram-positive cocci, not a gram-negative bacilli. It does not match the given description. D: Staphylococcus epidermidis - Staphylococcus epidermidis is also a gram-positive cocci, not a gram-negative bacilli. It does

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