A patient suffering from syphilis was prescribed a drug the action of which based upon disturbed generation of murein leading to death of the causative agent. What drug is it?

Correct Answer: A

Rationale: The correct answer is A: Benzylpenicillin sodium salt. Benzylpenicillin is a beta-lactam antibiotic that inhibits the synthesis of bacterial cell walls by disrupting the formation of murein (peptidoglycan), leading to bacterial cell death. This mechanism specifically targets the causative agent of syphilis, Treponema pallidum. - Choice B: Bijochinol is not a known drug used to treat syphilis. - Choice C: Ciprofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA replication and is not the first-line treatment for syphilis. - Choice D: Azithromycin is a macrolide antibiotic that interferes with bacterial protein synthesis and is commonly used to treat other infections but is not the preferred treatment for syphilis.

Correct Answer: A

Rationale: The correct answer is A: Escherichia coli. E. coli is the most common bacteria responsible for causing urinary tract infections due to its ability to adhere to the urinary tract lining and multiply rapidly. It is a normal inhabitant of the gut and can enter the urinary tract through improper hygiene practices. Salmonella enterica and Neisseria gonorrhoeae are typically associated with other infections like food poisoning and gonorrhea, respectively. Mycobacterium tuberculosis causes tuberculosis, not urinary tract infections. Thus, based on its prevalence and pathogenicity in the urinary tract, E. coli is the correct choice.

Correct Answer: C

Rationale: The correct answer is C: Pili. Pili are bacterial structures involved in conjugation, which is the process of transferring genetic material between bacterial cells. Pili facilitate the physical contact between donor and recipient cells, allowing for the transfer of plasmids or other genetic material. Capsules (choice A) are involved in protection and adherence, not conjugation. Flagella (choice B) are responsible for bacterial motility. Fimbriae (choice D) are also involved in adherence but not in conjugation. Therefore, the correct answer is C as pili specifically play a crucial role in the process of conjugation.

Correct Answer: D

Rationale: Step-by-step rationale: 1. Infectious process triggers an immune response to fight off the invading pathogen. 2. The immune response can lead to inflammation, fever, and production of antibodies. 3. Hypersensitivity reactions can also occur in response to the infection. 4. Options A, B, and C are not defining features of the infectious process. Summary: Option D is correct because an infectious process typically leads to an immune response and possibly hypersensitivity reactions. Options A, B, and C are incorrect as they do not specifically relate to the immune response or hypersensitivity reactions in the context of an infectious process.

Correct Answer: A

Rationale: The correct answer is A: Benzylpenicillin sodium salt. Benzylpenicillin is a beta-lactam antibiotic that inhibits the synthesis of bacterial cell walls by disrupting the formation of murein (peptidoglycan), leading to bacterial cell death. This mechanism specifically targets the causative agent of syphilis, Treponema pallidum. - Choice B: Bijochinol is not a known drug used to treat syphilis. - Choice C: Ciprofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA replication and is not the first-line treatment for syphilis. - Choice D: Azithromycin is a macrolide antibiotic that interferes with bacterial protein synthesis and is commonly used to treat other infections but is not the preferred treatment for syphilis.

Correct Answer: C

Rationale: The correct answer is C: Carry genes for antibiotic resistance. Bacterial plasmids are small, circular DNA molecules that can be transferred between bacteria, carrying genes such as antibiotic resistance. This allows bacteria to survive in the presence of antibiotics. Plasmids do not directly play a role in protein synthesis (choice A) or DNA replication (choice B). Plasmids are not responsible for motility (choice D) as that function is usually carried out by flagella or other cellular structures.

Correct Answer: D

Rationale: The correct answer is D (All of the above). All three bacteria (Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa) produce endotoxins that can lead to septic shock. Endotoxins are part of the outer membrane of Gram-negative bacteria and can trigger a strong immune response, leading to septic shock when released in large amounts. Escherichia coli and Salmonella enterica are common causes of bacterial septic shock, while Pseudomonas aeruginosa is known for its ability to produce endotoxins that contribute to severe infections and septic shock. Therefore, all three choices are correct in this context.

Correct Answer: D

Rationale: The correct answer is D: Thin mobile bacillus with central spore. This is because the causative agent of botulism, Clostridium botulinum, is a gram-positive bacillus that typically appears as a thin rod-shaped bacterium with a central endospore. This characteristic morphology is essential in the identification of Clostridium botulinum. A: Gram-positive bacillus with subterminal spore - This is incorrect as Clostridium botulinum typically has a central endospore, not a subterminal one. B: Thick gram-positive non-spore-forming bacillus - This is incorrect as Clostridium botulinum forms endospores, although they are not thick. C: Gram-positive bacillus with terminal spore - This is incorrect as the spore of Clostridium botulinum is typically central, not terminal.

Correct Answer: C

Rationale: The bacterial capsule is composed of polysaccharides. This outer layer helps bacteria evade the host immune system, protect against desiccation, and aid in attachment to host cells. Polysaccharides are long chains of sugar molecules, providing a protective barrier for the bacteria. Lipopolysaccharides (choice A) are found in the outer membrane of Gram-negative bacteria and are not a major component of the capsule. Teichoic acid (choice B) is a component of the cell wall in Gram-positive bacteria, not the capsule. Peptidoglycan (choice D) is another component of the cell wall but is not part of the capsule.