ATI RN
Pharmacology ATI Quizlet Questions
Question 1 of 5
A patient suffering from generalized anxiety disorder (GAD) has a history of drug dependence that includes the illicit use of secobarbital ('reds') and a variety of other drugs. Psychotherapy is indicated, but the physician also prescribes a drug that can be helpful in GAD and that has the advantage of no abuse liability. The drug prescribed was most likely to have been
Correct Answer: B
Rationale: Buspirone, a 5HT1A partial agonist, treats GAD by modulating serotonin without sedative or euphoric effects, making it ideal for patients with substance abuse histories like secobarbital (a barbiturate). It lacks abuse potential, unlike benzodiazepines, and doesn't cause dependence, aligning with the patient's needs. Bupropion, an NE/DA reuptake inhibitor, targets depression and smoking cessation, not GAD, and has stimulant-like risks. Baclofen, a GABA_B agonist, manages spasticity, not anxiety, and has some abuse potential. Buprenorphine, an opioid partial agonist, treats addiction but not GAD and carries dependence risk. Phenobarbital, a barbiturate, mirrors the patient's abuse history and is contraindicated. Buspirone's efficacy in GAD, non-addictive nature, and safety in this context make it the optimal choice.
Question 2 of 5
A 59-year-old man with hypertension, gastroesophageal reflux disorder, AIDS, seizure disorder, and depression is currently maintained on multiple medications, including propranolol. He does not have his medication list at his current office visit with his primary care physician. His blood pressure is 180/100 mm Hg. The patient states that he is taking all of his medications as scheduled. Which of the following drugs is the most likely explanation of this finding?
Correct Answer: D
Rationale: The patient's uncontrolled hypertension (180/100 mm Hg) despite propranolol, a β-blocker, suggests a drug interaction. Cimetidine , an H2 blocker, inhibits CYP2D6, but propranolol's metabolism is via CYP1A2/CYP2D6-effect is minimal. Fluoxetine and Paroxetine , SSRIs, also inhibit CYP2D6, but their impact on propranolol is less significant. Rifampin induces CYP enzymes, reducing propranolol levels, but isn't listed as likely. Ritonavir (E), a protease inhibitor for AIDS, potently inhibits CYP3A4 and CYP2D6, increasing propranolol levels, yet here it paradoxically fails to control BP, possibly due to complex polypharmacy or adherence issues. Ritonavir's interaction is most likely given his AIDS treatment, affecting propranolol's efficacy or metabolism, leading to this outcome.
Question 3 of 5
Before administering a nonselective adrenergic blocker, what should the nurse assess?
Correct Answer: A
Rationale: Monitor vital signs and assess cardiovascular status including pulse, blood pressure, and cardiac output to evaluate for possible cardiac effects. Although assessment of bowel sounds, appetite, serum albumin level, or serum sodium and potassium levels may be important to patient care, they are not related to administration of a nonselective adrenergic blocking agent. The nurse should prioritize cardiovascular assessments to ensure patient safety.
Question 4 of 5
A student nurse was asked by the nurse instructor to explain the procedure for the administration of erythromycin ointment to the eyes of the newborn. Which of the following statements made by the student indicates a need for further research?
Correct Answer: D
Rationale: After administering erythromycin ointment to the eyes of the newborn, there is no need to flush the eyes. The ointment is meant to be left in the eyes to provide protection against eye infections that can be acquired during birth. Flushing the eyes after instilling the ointment may reduce its effectiveness and is not part of the standard procedure. The ointment should be applied directly to the conjunctival sacs without rinsing or flushing the eyes.
Question 5 of 5
A patient suffering from generalized anxiety disorder (GAD) has a history of drug dependence that includes the illicit use of secobarbital ('reds') and a variety of other drugs. Psychotherapy is indicated, but the physician also prescribes a drug that can be helpful in GAD and that has the advantage of no abuse liability. The drug prescribed was most likely to have been
Correct Answer: B
Rationale: Buspirone, a 5HT1A partial agonist, treats GAD by modulating serotonin without sedative or euphoric effects, making it ideal for patients with substance abuse histories like secobarbital (a barbiturate). It lacks abuse potential, unlike benzodiazepines, and doesn't cause dependence, aligning with the patient's needs. Bupropion, an NE/DA reuptake inhibitor, targets depression and smoking cessation, not GAD, and has stimulant-like risks. Baclofen, a GABA_B agonist, manages spasticity, not anxiety, and has some abuse potential. Buprenorphine, an opioid partial agonist, treats addiction but not GAD and carries dependence risk. Phenobarbital, a barbiturate, mirrors the patient's abuse history and is contraindicated. Buspirone's efficacy in GAD, non-addictive nature, and safety in this context make it the optimal choice.