A patient suffering form tuberculosis was treated with rifampicin, which caused drug resistance of tuberculosis mycobacteria. In order to reduce mycobacteria resistance, rifampicin should be combined with the following drug:

Correct Answer: A

Rationale: The correct answer is A: Isoniazid. When rifampicin is used alone, there is a risk of developing resistance. Isoniazid is commonly used in combination with rifampicin to prevent resistance by targeting different mechanisms in the bacteria. Isoniazid works by inhibiting mycolic acid synthesis, while rifampicin targets RNA polymerase. This combination therapy is known as the first-line treatment for tuberculosis. Choices B, C, and D are incorrect because they do not have the same mechanism of action as isoniazid and would not be effective in preventing rifampicin resistance.

Correct Answer: A

Rationale: The correct answer is A: TRUE. The innate immune system is the body's first line of defense against infections and is always active, providing immediate protection without prior exposure to a specific pathogen. It includes physical barriers, such as skin and mucous membranes, and cellular components like phagocytes and natural killer cells. The innate immune response is nonspecific and rapid, providing a crucial initial defense against pathogens. Choice B is incorrect because the innate immune system is always active, even without any prior exposure to pathogens. Choice C is incorrect because the innate immune system is consistently functioning to protect the body, regardless of the situation. Choice D is incorrect as the correct answer is A.

Correct Answer: A

Rationale: The correct answer is A: mRNA. mRNA carries the genetic code from the DNA in the cell nucleus to the ribosomes in the cytoplasm, where protein synthesis occurs. It serves as a template for protein synthesis by specifying the order of amino acids. tRNA (choice B) brings amino acids to the ribosome during protein synthesis. rRNA (choice C) is a structural component of ribosomes. snRNA (choice D) is involved in RNA processing and splicing, not protein synthesis. Therefore, choice A is correct as it directly carries the genetic code for protein synthesis.

Correct Answer: A

Rationale: Rationale: Staphylococci are gram-positive bacteria that typically arrange in clusters resembling a bunch of grapes. This characteristic morphology is specific to staphylococci due to their division pattern. Sarcina, Tetracocci, and Candida fungi do not exhibit this clustering pattern. Staphylococci are commonly associated with purulent infections, making them the most likely microorganisms in this scenario.

Correct Answer: B

Rationale: The correct answer is B: Halophiles. Halophiles are bacteria that can survive in extreme salty environments. They have adapted to thrive in high salt concentrations. Psychrophiles (A) thrive in cold temperatures, Thermophiles (C) thrive in high temperatures, and Mesophiles (D) thrive in moderate temperatures. Therefore, they are not adapted to survive in extreme salty environments like Halophiles.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. 1. Gram-positive cocci in chains suggest streptococci. 2. Catalase-negative indicates it's not staphylococci. 3. Beta-hemolytic points towards Group A Streptococcus (S. pyogenes). Summary: B. Streptococcus pneumoniae is not beta-hemolytic. C. Enterococcus faecalis is not typically chains. D. Staphylococcus aureus is catalase-positive.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pneumoniae. This bacterium is the most common cause of bacterial pneumonia in adults. It is a leading cause of community-acquired pneumonia. Streptococcus pneumoniae is known for its ability to infect the respiratory tract and cause inflammation in the lungs leading to pneumonia. Mycobacterium tuberculosis causes tuberculosis, not pneumonia. Escherichia coli is associated with urinary tract infections and gastrointestinal illnesses, not pneumonia. Clostridium botulinum causes botulism, a severe form of food poisoning, but not pneumonia. Therefore, the correct choice is Streptococcus pneumoniae as it is specifically known for causing pneumonia.

Correct Answer: B

Rationale: The correct answer is B: Macrolides. Listeriosis is typically treated with antibiotics such as Penicillin and ampicillin due to their effectiveness against Listeria monocytogenes. Macrolides, on the other hand, are not first-line agents for listeriosis treatment. They are less effective in treating this bacterial infection compared to Penicillin and ampicillin. Cephalosporins may also be less effective against Listeria monocytogenes compared to Penicillin and ampicillin. Choice D is incorrect as Macrolides are not suitable for listeriosis treatment.

Correct Answer: A

Rationale: The correct answer is A: Entamoeba histolytica. This protozoon is responsible for causing amoebic dysentery, which presents with bloody diarrhea. The "raspberry jelly" appearance of stool is due to the presence of mucosal lining and blood. The large mononuclear cells with absorbed red blood cells are characteristic of the histopathology of Entamoeba histolytica infection. Giardia lamblia (B) causes watery diarrhea, not bloody stools. Campylobacter jejuni (C) is a bacterial pathogen associated with gastroenteritis, but does not typically cause bloody diarrhea. Toxoplasma gondii (D) causes toxoplasmosis, a systemic infection with symptoms such as fever and lymphadenopathy, but not bloody diarrhea.