ATI RN
Endocrine Pharmacology Quizlet Questions
Question 1 of 4
A patient presents with tiredness, weakness, anorexia, apathy, abdominal pain, hyperpigmentation and postural hypertension. Upon infection he appears to be in cardiogenic shock and his blood volume is depleted. His sodium levels are low, potassium levels are high. Which of the following would also be elevated?
Correct Answer: D
Rationale: Addison's disease (adrenal insufficiency) causes hyperpigmentation, hyponatremia, hyperkalemia, and shock due to low cortisol; ACTH is elevated due to lack of negative feedback.
Question 2 of 4
A patient presents with rhabdomyolysis and depletion of 2-3-diphosphoglycerate. A common complication of high levels of the molecule being affected in this patient would be:
Correct Answer: A
Rationale: Rhabdomyolysis releases phosphate, depleting 2,3-DPG and raising serum phosphate, leading to hyperphosphatemia and metastatic calcification.
Question 3 of 4
Which of the following drugs has potent antiandrogenic and weak progestational activity?
Correct Answer: D
Rationale: None of the listed options are correct; likely intended to be cyproterone acetate, not listed.
Question 4 of 4
A young man presents with a blood pressure of 175 /110mmHg. He is found to have a high circulating aldosterone but a low circulating cortisol. Glucocorticoid treatment lowers his circulating aldosterone and lowers his blood pressure to 140 /85mm Hg. He probably has an abnormal
Correct Answer: A
Rationale: 17?-hydroxylase deficiency causes low cortisol, high mineralocorticoids (e.g., DOC), and hypertension; glucocorticoid therapy suppresses ACTH, reducing aldosterone.