ATI RN
Endocrine Pharmacology Quizlet Questions
Question 1 of 5
A patient presents with rhabdomyolysis and depletion of 2-3-diphosphoglycerate. A common complication of high levels of the molecule being affected in this patient would be:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
A young man presents with a blood pressure of 175 /110mmHg. He is found to have a high circulating aldosterone but a low circulating cortisol. Glucocorticoid treatment lowers his circulating aldosterone and lowers his blood pressure to 140 /85mm Hg. He probably has an abnormal
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following signaling pathways likely mediates the therapeutic efficacy of oxytocin during labor induction?
Correct Answer: A
Rationale: The correct answer is A: Cyclic adenosine monophosphate (cAMP) synthesis. Oxytocin induces uterine contractions during labor by binding to its receptor and activating the G-protein coupled receptor, leading to increased cAMP synthesis. This results in the activation of protein kinase A, which ultimately leads to smooth muscle contraction in the uterus. Phosphoinositide hydrolysis (choice B) is not involved in oxytocin signaling. Cyclic guanosine monophosphate (cGMP) synthesis (choice C) is typically associated with nitric oxide signaling, not oxytocin. Tyrosine residue phosphorylation (choice D) is more related to growth factor signaling pathways, not oxytocin-induced labor contractions.
Question 4 of 5
Which of the following drugs would be appropriate for this patient while waiting for radiotherapy to work?
Correct Answer: D
Rationale: The correct answer is D: Octreotide. This drug is appropriate for the patient as it helps manage symptoms of carcinoid syndrome while waiting for radiotherapy to take effect. Octreotide is a somatostatin analog that inhibits the release of various hormones, providing symptom relief. Leuprolide (A) is a gonadotropin-releasing hormone agonist used for hormone-related cancers, not specifically for symptom management. Cosyntropin (B) is a synthetic adrenocorticotropic hormone used for diagnosing adrenal insufficiency. Somatropin (C) is human growth hormone used for growth disorders, not symptom management in cancer patients.
Question 5 of 5
Which of the following cell elements represent the main site of therapeutic action of levothyroxine?
Correct Answer: D
Rationale: The correct answer is D: Cell nucleus. Levothyroxine acts by binding to thyroid hormone receptors in the cell nucleus, where it regulates gene expression. This is essential for controlling metabolism and energy production. Choices A, B, and C are incorrect because levothyroxine's mechanism of action does not involve the cell membrane, mitochondria, or smooth endoplasmic reticulum. The nucleus is where genetic material is stored and gene expression is controlled, making it the main site of action for levothyroxine.