ATI RN
Endocrine Pharmacology Quizlet Questions
Question 1 of 5
A patient presents with lethargy, tiredness, cold intolerance, dryness of skin and hair, hoarsness of voice and weight gain. He also has psychosis and his heart rate appears to be lower than normal. Which of the following is not associated with the presenting symptoms?
Correct Answer: D
Rationale: Hypothyroidism symptoms (lethargy, weight gain, etc.) are linked to Hashimoto's, cretinism, and iodine deficiency (low thyroid hormone). Increased iodine levels would cause hyperthyroidism, not these symptoms.
Question 2 of 5
A girl presents with delayed puberty, absent secondary sexual characteristics, and primary amenorrhea. She also appears to be hypertensive and hypokalemia. Which of the following enzymes is increased if there is virilization of a person?
Correct Answer: C
Rationale: 21-hydroxylase deficiency (CAH) causes hypertension, hypokalemia, and virilization (increased androgens) due to shunting from cortisol to androgen synthesis.
Question 3 of 5
A patient presents with rhabdomyolysis and depletion of 2-3-diphosphoglycerate. A common complication of high levels of the molecule being affected in this patient would be:
Correct Answer: A
Rationale: Rhabdomyolysis releases phosphate, depleting 2,3-DPG and raising serum phosphate, leading to hyperphosphatemia and metastatic calcification.
Question 4 of 5
Which of the following drugs has potent antiandrogenic and weak progestational activity?
Correct Answer: D
Rationale: None of the listed options are correct; likely intended to be cyproterone acetate, not listed.
Question 5 of 5
A young man presents with a blood pressure of 175 /110mmHg. He is found to have a high circulating aldosterone but a low circulating cortisol. Glucocorticoid treatment lowers his circulating aldosterone and lowers his blood pressure to 140 /85mm Hg. He probably has an abnormal
Correct Answer: A
Rationale: 17?-hydroxylase deficiency causes low cortisol, high mineralocorticoids (e.g., DOC), and hypertension; glucocorticoid therapy suppresses ACTH, reducing aldosterone.