A patient presents with a target-like rash with concentric erythematous rings and central clearing on the trunk and extremities. The patient reports recent exposure to a new medication. Which of the following conditions is most likely responsible for this presentation?

Correct Answer: A

Rationale: Erythema multiforme is a skin condition characterized by the sudden onset of a target-like rash with concentric erythematous rings and central clearing on the trunk and extremities. It typically presents with a distinctive "iris" or "bull's eye" pattern. Erythema multiforme is often triggered by exposure to certain medications, such as antibiotics, anticonvulsants, and other drugs. The rash is usually accompanied by symptoms like fever, malaise, and joint pain. It is important to identify and discontinue the offending medication causing the reaction in cases of drug-induced erythema multiforme.

Correct Answer: C

Rationale: Vocal cord nodules are benign growths on the vocal cords, typically caused by vocal abuse or misuse. The most appropriate intervention for managing vocal cord nodules is voice therapy and vocal hygiene education. Voice therapy aims to correct vocal habits and techniques that contribute to the formation of nodules, while vocal hygiene education focuses on maintaining vocal health through proper hydration, rest, and avoiding behaviors that strain the vocal cords. These interventions have been shown to be effective in reducing and eliminating vocal cord nodules without the need for surgical intervention. Surgery, such as vocal cord polypectomy or injection with corticosteroids, is typically reserved for cases that do not respond to conservative management or if there are significant complications. Partial laryngectomy is a more extensive surgical procedure that is not typically indicated for vocal cord nodules.

Correct Answer: D

Rationale: The presentation of a small, painless, well-defined nodule on the lateral aspect of the neck, above the clavicle, along with the cytology showing clusters of polygonal cells with abundant granular cytoplasm is most indicative of a parathyroid adenoma. Parathyroid adenomas are benign tumors derived from the parathyroid gland that can produce excess parathyroid hormone (PTH), leading to hyperparathyroidism. The characteristic histology of parathyroid adenomas includes chief cells with abundant granular cytoplasm.

Correct Answer: A

Rationale: The sudden onset of severe vertigo, nausea, vomiting, and nystagmus in a patient with a recent upper respiratory tract infection is highly suggestive of vestibular neuritis. Vestibular neuritis is typically caused by inflammation of the vestibular nerve, often following a viral infection such as an upper respiratory tract infection. This condition presents with acute, severe, continuous vertigo without associated hearing loss. The presence of nystagmus, along with the absence of hearing loss, helps differentiate vestibular neuritis from Meniere's disease (which typically presents with episodic vertigo, hearing loss, and tinnitus) and acoustic neuroma (which presents with gradual onset of symptoms including unilateral hearing loss, tinnitus, and imbalance). Benign paroxysmal positional vertigo (BPPV) typically presents with brief episodes of vertigo triggered by specific head movements, rather than the continuous vertigo seen in this case.

Correct Answer: A

Rationale: The presentation described is characteristic of acute angle-closure glaucoma. This condition typically presents with sudden-onset severe eye pain, headache, nausea, and vomiting. On examination, the affected eye may appear red due to conjunctival injection, and there may be a steamy cornea due to corneal edema. The mid-dilated, non-reactive pupil is a key finding in angle-closure glaucoma, as the iris bombe (forward movement of the peripheral iris) blocks the drainage angle, leading to increased intraocular pressure. If left untreated, acute angle-closure glaucoma can result in irreversible vision loss. Immediate intervention is crucial to lower the intraocular pressure and prevent further damage to the optic nerve. Prompt referral to an ophthalmologist for definitive treatment is necessary in cases of suspected acute angle-closure glaucoma.