ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
A patient on antibacterial therapy has to do an operation in which a skeletal muscle relaxant may be used. He will be at risk if this antimicrobial is:
Correct Answer: B
Rationale: Aminoglycosides (e.g., gentamicin) potentiate neuromuscular blockade, risking respiratory depression with muscle relaxants.
Question 2 of 5
A man with a history of multiple antibiotic resistance is given a prophylactic IV dose of antibiotic before surgery. As the antibiotic is being infused, the patient becomes flushed over most of his body. Which of the following antibiotics is most likely responsible?
Correct Answer: C
Rationale: Vancomycin causes ‘red man syndrome’ (flushing) due to histamine release if infused too rapidly.
Question 3 of 5
A patient develops severe, watery diarrhea, fever & abdominal pain. Clostridium difficile infection in the gut is confirmed. The antimicrobial therapy for this antibiotic-associated pseudomembranous colitis is:
Correct Answer: D
Rationale: Metronidazole or vancomycin treats C. difficile colitis; vancomycin is preferred for severe cases, and both are effective.
Question 4 of 5
Which of the following is the most effective agent in the treatment of Rickettsia, Mycoplasma, and Chlamydia infections?
Correct Answer: D
Rationale: Tetracycline (e.g., doxycycline) is effective against intracellular pathogens like Rickettsia, Mycoplasma, and Chlamydia.
Question 5 of 5
Hypersensitivity reaction is a common and serious complication to:
Correct Answer: D
Rationale: Penicillins and sulfonamides frequently cause hypersensitivity reactions (e.g., rash, anaphylaxis), unlike erythromycin.