A patient is taking the urinary antiseptic methenamine for a urinary tract infection (UTI). The nurse understands that this drug should not be given concurrently with which other drug to avoid crystalluria?

Correct Answer: D

Rationale: Methenamine, which is a urinary antiseptic used to treat UTIs, can cause crystalluria when taken concurrently with drugs that have an acidic pH, such as trimethoprim-sulfamethoxazole. Trimethoprim-sulfamethoxazole can lower the pH of urine, leading to the formation of crystals in the urine which can potentially result in kidney damage. Therefore, it is important to avoid giving methenamine concurrently with trimethoprim-sulfamethoxazole to prevent this adverse effect.

Correct Answer: C

Rationale: Iodides (NaI and KI) are given before thyroidectomy to decrease the size and vascularity of the hyperplastic thyroid gland. This reduction in vascularity minimizes the risk of excessive bleeding during surgery. By shrinking the gland and reducing blood flow, iodides make the surgical procedure safer and more manageable. This preoperative preparation is crucial for ensuring a successful thyroidectomy with minimal complications.

Correct Answer: D

Rationale: Budesonide is more effective when applied topically because it has poor cell membrane permeability, allowing it to remain localized at the site of application. This makes it particularly useful for treating severe eczema and other inflammatory skin conditions. Its localized action minimizes systemic side effects, making it a safer option for long-term topical use compared to other glucocorticoids.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.