ATI RN
RN ATI Capstone Pharmacology 2 Quiz Questions
Question 1 of 9
A patient is taking azithromycin. Which nursing intervention(s) would the nurse plan to implement for this patient? (Select all that apply.)
Correct Answer: A
Rationale: Azithromycin is a macrolide antibiotic that can cause hepatotoxicity, so periodic liver function tests are necessary. Intravenous azithromycin should be diluted as per protocol, typically in 250-500 mL of fluid, not 50 mL. Loose stools or diarrhea may indicate Clostridium difficile-associated diarrhea, a serious adverse effect. Superinfections, such as oral thrush or vaginal yeast infections, should be reported promptly. Teaching the patient to take the oral drug 1 hour before or 2 hours after meals ensures optimal absorption. Avoiding antacids around the time of administration prevents interference with absorption.
Question 2 of 9
During an infusion of albumin, the nurse monitors the patient closely for the development of which adverse effect?
Correct Answer: C
Rationale: Albumin is a plasma protein that helps maintain the oncotic pressure in the blood vessels and prevents fluid from leaking out into the tissues. During an infusion of albumin, there is a risk of fluid volume overload, especially in patients with existing heart failure or kidney disease. The nurse must monitor the patient closely for signs and symptoms of fluid volume overload, such as edema, shortness of breath, crackles in the lungs, and increased blood pressure. Prompt recognition and management of fluid volume overload are essential to prevent complications such as pulmonary edema and worsening heart failure. Hypernatremia and fluid volume deficit are unlikely to occur during an albumin infusion, and a transfusion reaction is not associated with albumin administration.
Question 3 of 9
What is the administration route of Penicillin in adults?
Correct Answer: B
Rationale: Penicillin is typically administered to adults intravenously (IV) when a rapid onset of action is needed, such as in cases of severe infections or when the medication needs to reach high concentrations in the bloodstream quickly to be effective. Intravenous administration allows for immediate delivery of the medication directly into the bloodstream, ensuring efficient and quick distribution throughout the body.
Question 4 of 9
Drugs used as premedication to General Anesthesia to reduce secretions:
Correct Answer: A
Rationale: Anticholinergic drugs are commonly used as premedication to general anesthesia to reduce secretions. These medications work by blocking the action of acetylcholine, a neurotransmitter that stimulates secretions in the body. By inhibiting this action, anticholinergics help in reducing respiratory secretions, saliva, and other bodily fluids during anesthesia induction and maintenance. This can help prevent complications such as airway obstruction and aspiration during the surgical procedure. Examples of commonly used anticholinergic drugs for this purpose include atropine and glycopyrrolate.
Question 5 of 9
A patient has been taking a beta blocker for 4 weeks as part of his antianginal therapy. He also has type II diabetes and hyperthyroidism. When discussing possible adverse effects, the nurse will include which information?
Correct Answer: D
Rationale: The correct information to include when discussing possible adverse effects of beta blockers with a patient who has type II diabetes and hyperthyroidism is to "Monitor your blood glucose levels for possible hypoglycemia or hyperglycemia." Beta blockers can mask the signs of hypoglycemia (low blood sugar) in patients with diabetes by suppressing the sympathetic nervous system response to low blood sugar. This can lead to a delay in recognizing and treating hypoglycemia, which can be dangerous for diabetic patients. Additionally, beta blockers can also affect glucose metabolism and potentially worsen hyperglycemia in patients with diabetes. Therefore, close monitoring of blood glucose levels is essential to manage these potential adverse effects and adjust the treatment regimen as needed.
Question 6 of 9
When reading about a drug, the nurse learns it has a median toxic dose of 50 mg. The patient has been receiving 60 mg of the drug. What analysis does the nurse make?
Correct Answer: C
Rationale: Median toxic dose (TD50) is where 50% show toxicity-60 mg exceeds this, raising adverse effect risk (e.g., toxicity signs), not lethality for all. Effect may persist, not fail. Efficacy/potency are defined, just exceeded. Lethal dose (LD50) differs-60 mg isn't half lethal. Excess drives risk, per pharmacodynamics.
Question 7 of 9
Sedatives and hypnotics are drugs which act as:
Correct Answer: A
Rationale: Sedatives and hypnotics are drugs that belong to the class of central nervous system depressants. These drugs work by slowing down the activity of the brain and the central nervous system, leading to a calming or sedative effect. They are commonly prescribed to induce sleep (hypnotics) or reduce anxiety (sedatives) by depressing the excitability of nerve cells. This property makes them effective in producing sedation, relaxation, and sleep in individuals. Therefore, the correct classification for sedatives and hypnotics is as depressants.
Question 8 of 9
A 56-year-old man with progressive, chronic renal impairment is awaiting renal replacement therapy. His treatment includes calcium carbonate tablets, furosemide, irbesartan and amlodipine. He is admitted severely unwell with a BP of 40 by palpation, pulse 112. An ECG shows a broad complex tachycardia with no P waves. Serum Ca2+ is 2.3 mmol/L, PO4 1.7 mmol/L, creatinine 785 μmol/L, Na+ 142 mmol/L, K+ 7.4 mmol/L. Which of the following would be appropriate management?
Correct Answer: C
Rationale: Severe hyperkalemia (K+ 7.4 mmol/L) in renal failure causes broad complex tachycardia, risking arrest. Amiodarone treats arrhythmias but not hyperkalemia's cause. Digoxin is contraindicated in hyperkalemia and renal failure. IV calcium gluconate stabilizes cardiac membranes, countering potassium's depolarizing effect, appropriate immediate management. Pacing or colestyramine (potassium binder) are secondary. Calcium's rapid action protects the heart, buying time for dialysis, critical in this life-threatening scenario.
Question 9 of 9
How can Ondansetron be administered? Select all that apply.
Correct Answer: A
Rationale: Ondansetron, commonly used to prevent nausea and vomiting, can be administered either orally (PO) or intravenously (IV). Both routes of administration are effective in delivering the medication to achieve the desired therapeutic effects. While options C (Subcutaneous) and D (IM) are not typically used for ondansetron administration, the correct answers are A (PO) and B (IV).