A patient is taking azithromycin. Which nursing intervention(s) would the nurse plan to implement for this patient? (Select all that apply.)

Correct Answer: A

Rationale: Azithromycin is a macrolide antibiotic that can cause hepatotoxicity, so periodic liver function tests are necessary. Intravenous azithromycin should be diluted as per protocol, typically in 250-500 mL of fluid, not 50 mL. Loose stools or diarrhea may indicate Clostridium difficile-associated diarrhea, a serious adverse effect. Superinfections, such as oral thrush or vaginal yeast infections, should be reported promptly. Teaching the patient to take the oral drug 1 hour before or 2 hours after meals ensures optimal absorption. Avoiding antacids around the time of administration prevents interference with absorption.

Correct Answer: B

Rationale: Trimethoprim inhibits dihydrofolate reductase, not activates it, blocking folate synthesis in bacteria, so that's false. It's a weak base, a true statement, aiding its concentration in acidic environments like urine. It has good prostate penetration, effective in prostatitis, making that false. It distributes into CSF, useful in meningitis, so that's incorrect. It's teratogenic, not harmless in pregnancy. Its basic nature enhances its antibacterial efficacy, a key pharmacokinetic advantage in urinary tract infections.

Correct Answer: C

Rationale: One major side effect to monitor in a patient taking Lithium for bipolar I disorder is the risk of seizures. Lithium is known to lower the seizure threshold, increasing the likelihood of seizures occurring, especially if the patient has any pre-existing risk factors for seizures. Therefore, it is critical to closely monitor patients on Lithium for any signs or symptoms of seizures and promptly address them if they occur to prevent any complications. Monitoring lithium levels and maintaining them within the therapeutic range can also help reduce the risk of seizures.

Correct Answer: D

Rationale: Learning a representative (prototype) drug from each antibiotic class simplifies understanding by focusing on shared traits-mechanisms, effects, and side effects-reducing the burden of memorizing every drug. Mnemonics aid recall but don't teach concepts. Flow charts organize but lack depth. Categorizing is broad, while prototypes offer a practical, foundational approach, widely used in pharmacology education for mastery.

Correct Answer: A

Rationale: Sedatives and hypnotics are drugs that belong to the class of central nervous system depressants. These drugs work by slowing down the activity of the brain and the central nervous system, leading to a calming or sedative effect. They are commonly prescribed to induce sleep (hypnotics) or reduce anxiety (sedatives) by depressing the excitability of nerve cells. This property makes them effective in producing sedation, relaxation, and sleep in individuals. Therefore, the correct classification for sedatives and hypnotics is as depressants.