ATI RN
Safety Pharmacology Across the Lifespan Questions
Question 1 of 5
A patient is presented with weakness of legs, arms, trunk, tingling and numbness that progressively worsens. Peripheral blood smear shows macrocytic anemia. Which of the following is not the factor causing this condition?
Correct Answer: D
Rationale: The symptoms (weakness, tingling, numbness) and macrocytic anemia suggest vitamin B12 deficiency, often causing subacute combined degeneration of the spinal cord. Chronic atrophic gastritis (A), ileal resection (B), tapeworm infestation (C), and alcoholism (D) all impair B12 absorption or metabolism. Exposure to nitrous oxide (E) inactivates B12, causing similar symptoms, but it’s an external factor, not a chronic condition like the others, making it the least fitting as a 'factor causing this condition.'
Question 2 of 5
RBCs break into fragments, they are referred to as schistocytes. These type of cells are seen in
Correct Answer: C
Rationale: Schistocytes (fragmented RBCs) are hallmark of microangiopathic hemolytic anemia (MAHA, B), e.g., TTP or DIC, due to mechanical shearing. Thalassemia (A) shows target cells, ITP (C) is thrombocytopenia without schistocytes, Gilbert’s syndrome (D) is benign hyperbilirubinemia—MAHA fits. Note: C seems a typo for B based on options.
Question 3 of 5
What’s the most appropriate test to diagnose haemophilia?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
The testicular lobules:
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
The following statements about the prostate are true:
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.