ATI RN
Intro to Pharmacology ATI Quizlet Questions
Question 1 of 5
A patient is admitted to the hospital with multidrug-resistant urinary tract infection. Laboratory tests show Pseudomonas aeruginosa. Colistimethate sodium is ordered by intramuscular injection. The nurse understands that which of the following is the purpose for this drug?
Correct Answer: B
Rationale: Colistimethate sodium is a polymyxin antibiotic used to treat multidrug-resistant Gram-negative infections, including Pseudomonas aeruginosa. It is not safe for patients with renal impairments and does not prevent antibiotic resistance. Its primary purpose is to treat infections caused by resistant Gram-negative bacteria.
Question 2 of 5
The nurse is reviewing the client's history who is about to take Methotrexate. Which of the following drugs can be safely administered together with methotrexate?
Correct Answer: B
Rationale: Folic acid supplementation is recommended for patients on methotrexate to reduce the risk of side effects such as mucositis and myelosuppression. Tetracycline, sulfamethoxazole, and phenytoin can interact with methotrexate, increasing its toxicity. Folic acid helps mitigate these adverse effects without interfering with the drug's efficacy.
Question 3 of 5
Which route should lithium be administered by?
Correct Answer: A
Rationale: Lithium is typically administered orally (PO) for long-term treatment of bipolar disorder. However, in emergency situations or cases of lithium toxicity where rapid control of symptoms is required, lithium can be administered via the intravenous (IV) route for faster absorption and effectiveness. IV administration allows for quick delivery of the medication directly into the bloodstream to achieve therapeutic levels promptly. It is essential to closely monitor lithium levels and kidney function when administering it intravenously to prevent potential complications.
Question 4 of 5
Absorption, distribution, metabolism and excretion is the study of herdrugs':
Correct Answer: B
Rationale: Pharmacokinetics is the study of how drugs are absorbed, distributed, metabolized, and excreted by the body. These processes determine the concentration of a drug at its site of action and contribute to understanding the drug's effectiveness and potential side effects. Therefore, absorption, distribution, metabolism, and excretion are key components of pharmacokinetics. Pharmacodynamics (Choice A) refers to the study of the physiological effects of drugs and their mechanisms of action, which is different from the processes involved in drug movement through the body. Therapeutic action (Choice C) refers to the desired effects of a drug in treating a specific condition, rather than the processes involved in drug processing in the body. Pharmaceutical preparation (Choice D) is related to the formulation and development of drugs before their administration, not to the processes within the body. Toxic effect (Choice E) refers to the harmful effects of drugs, which can result from various factors including pharmacokin
Question 5 of 5
A patient is in the emergency department with new-onset atrial fibrillation. Which order for digoxin would most likely have the fastest therapeutic effect?
Correct Answer: D
Rationale: In a patient with new-onset atrial fibrillation who requires rapid initiation of digoxin therapy, the fastest therapeutic effect would be achieved by administering the loading dose intravenously. Option D (Digoxin 1 mg IV push now; then 0.25 mg IV daily) includes an initial IV loading dose of 1 mg, followed by a maintenance dose of 0.25 mg IV daily. IV administration allows for quicker absorption and onset of action compared to oral administration. This loading dose increases the digoxin concentration in the bloodstream more rapidly, leading to a quicker therapeutic effect. Subsequent maintenance doses can then be given orally for long-term management.