ATI RN
Pharmacology ATI Test Bank Questions
Question 1 of 5
A patient is admitted to the hospital with an acute gout attack. The nurse expects that which medication will be ordered to treat acute gout?
Correct Answer: A
Rationale: Colchicine is the medication of choice for treating acute gout attacks due to its anti-inflammatory properties. It works by inhibiting microtubule polymerization, which reduces the migration of neutrophils to the inflamed joint, thereby alleviating pain and swelling. Allopurinol and probenecid are used for long-term management of gout to prevent future attacks by lowering uric acid levels, but they are not effective during an acute attack. Sulfinpyrazone is another uricosuric agent used for chronic management. Therefore, colchicine is the most appropriate medication for acute gout treatment, and nurses should be familiar with its use and monitoring.
Question 2 of 5
A client with osteoporosis is asking the nurse regarding the use of Salmon calcitonin (Miacalcin) nasal spray. The nurse tells the client to do the following, except?
Correct Answer: B
Rationale: Repeating the dose if the spray is not felt is incorrect and can lead to overdose. The delivery system is designed for 30 doses, and unused solution should be discarded. Miacalcin is typically administered as one spray daily in one nostril. Vitamin D supplementation may be recommended to support bone health, but it is not a direct instruction for using Miacalcin.
Question 3 of 5
Methylergonovine (Methergine) is prescribed to a patient who is having postpartum bleeding. Prior to giving the medication, the nurse contacts the physician who prescribed the medication if which of the following condition is documented in the patient’s chart?
Correct Answer: C
Rationale: Methylergonovine (Methergine) is contraindicated in patients with ischemic heart disease because it can cause vasoconstriction, increasing the risk of myocardial infarction or other cardiac complications. Hypotension is not a contraindication, and uterine atony is the indication for the medication. Acute gastroenteritis is unrelated to the use of methylergonovine. Therefore, ischemic heart disease is the condition that requires the nurse to contact the physician.
Question 4 of 5
A 62-year-old woman with type 2 diabetes, hypertension, renal impairment (creatinine 146 μmol/L) and mild congestive cardiac failure has poor diabetic control (HbA1c = 10.5 per cent), despite treatment with maximum doses of a sulfonylurea. Her body mass index (BMI) is 26. Which of the following would be most appropriate pharmacotherapy?
Correct Answer: A
Rationale: Poor glycemic control (HbA1c 10.5%) despite max sulfonylurea in type 2 diabetes with renal impairment and CHF needs escalation. Insulin replaces sulfonylurea, offering precise control without renal clearance issues, most appropriate here. Rosiglitazone risks fluid retention, worsening CHF. Bisoprolol, a beta-blocker, and rimonabant (withdrawn) don't address glycemia. Metformin is contraindicated with creatinine 146 μmol/L (eGFR <30-45) due to lactic acidosis risk. Insulin's flexibility and safety in this complex case optimize outcomes, critical for reducing complications.
Question 5 of 5
Local anaesthetic agents:
Correct Answer: D
Rationale: Local anesthetics (e.g., lidocaine) block sodium channels, not potassium, halting depolarization, so that's false. They prevent depolarization, not repolarization, making that false. Vasoconstrictors (e.g., epinephrine) prolong action, not vasodilators, which shorten it, so that's incorrect. High extracellular potassium enhances activity by depolarizing membranes closer to threshold, a true statement. High calcium reduces efficacy by stabilizing membranes. The potassium effect is a subtle but real modulator of anesthetic potency, relevant in tissue conditions.