ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
A patient in their early 20s presents with recurrent bacterial infections. Lab work shows B cells in the periphery as well as low immunoglobulin levels. History shows immunoglobulin levels have decreased with age. Which of the following is the most likely?
Correct Answer: D
Rationale: Common variable immunodeficiency (CVID) presents with low immunoglobulin levels and recurrent infections, often manifesting in young adults.
Question 2 of 5
Which cytokine is essential for T-cell proliferation and is also necessary for the production of CD25-positive regulatory T cells?
Correct Answer: A
Rationale: IL-2 is critical for T-cell proliferation and the development of CD25+ regulatory T cells, which express the IL-2 receptor alpha chain (CD25).
Question 3 of 5
A graft between members of the same species is termed an?
Correct Answer: A
Rationale: An autograft is a transplant within the same individual (same species and genetic identity), though the answer 'A' seems inconsistent with typical definitions where 'allograft' (D) is more common for same-species grafts. Assuming a typo in the source.
Question 4 of 5
A patient suffering from recurrent mucosal infections and celiac disease. Turns out he is affected with a primary immunodeficiency. He is most probably affected with...?
Correct Answer: B
Rationale: IgA deficiency is a common primary immunodeficiency associated with recurrent mucosal infections and linked to autoimmune conditions like celiac disease.
Question 5 of 5
Mature naive B cells...?
Correct Answer: B
Rationale: Mature naive B cells co-express IgM and IgD on their surface, preparing them to respond to antigens.