A patient ill with amebiasis was prescribed a certain drug. The use of alcohol together with this drug is contraindicated because the drug inhibits metabolism of ethyl alcohol. What drug is it?

Correct Answer: A

Rationale: Rationale: 1. Metronidazole is known to inhibit aldehyde dehydrogenase, an enzyme involved in alcohol metabolism. 2. Inhibition of this enzyme leads to accumulation of acetaldehyde, causing unpleasant symptoms when alcohol is consumed. 3. This reaction is known as the disulfiram-like reaction. 4. Reserpine, Clonidine, and Diazepam do not have this specific mechanism of action. Summary: - Option A (Metronidazole) is correct due to its inhibition of alcohol metabolism. - Options B, C, and D are incorrect as they do not exhibit this interaction with alcohol metabolism.

Correct Answer: C

Rationale: The correct answer is C: Campylobacter jejuni. This bacterium is Gram-negative and comma-shaped, commonly causing respiratory infections. Vibrio cholerae (A) causes cholera, not respiratory infections. Shigella dysenteriae (B) causes dysentery, not respiratory infections. Helicobacter pylori (D) is associated with gastric ulcers, not respiratory infections. Therefore, Campylobacter jejuni is the most likely causative agent based on the given information.

Correct Answer: C

Rationale: The correct answer is C: Actinomycosis. Actinomycosis is a chronic suppurative bacterial infection caused by Actinomyces species, which form sulfur granules in purulent masses surrounded by dense fibrous tissue. In this case, the presence of fungal druses, plasma cells, xanthoma cells, and macrophages in the histological examination is characteristic of actinomycosis. The clinical presentation of skin redness, swelling, and abscess formation in the neck area also aligns with actinomycosis. Choice A: Syphilis is caused by Treponema pallidum, presenting with a painless chancre at the site of infection, not skin redness and swelling in the neck area. Choice B: Carbuncle is a bacterial skin infection involving a group of hair follicles, typically on the back of the neck, not characterized by fungal druses or sulfur granules. Choice D: Leprosy

Correct Answer: A

Rationale: Step-by-step rationale: 1. Family Retroviridae is known for having a single-stranded RNA genome. 2. The (-) sign indicates that the RNA strand is negative-sense. 3. Therefore, the correct answer A, "Their capsid consists of two copies of ssRNA(-)," is accurate. Summary: - Choice B is incorrect because Retroviridae have simple type of symmetry. - Choice C is incorrect as Retroviridae are not enveloped viruses. - Choice D is incorrect because Retroviridae are enveloped viruses.

Correct Answer: D

Rationale: The correct answer is D because the flu vaccine primarily stimulates systemic immunity rather than local immunity. It is administered parenterally (C) as it is injected into the body. It is a subunit vaccine (B) as it contains only specific antigens of the virus. It is a recommended vaccine (A) due to its effectiveness in preventing influenza. In summary, D is the correct choice as the flu vaccine mainly targets systemic immunity, not local immunity, unlike the other characteristics listed.

Correct Answer: B

Rationale: The correct answer is B: Mefloquine. Mefloquine is a histoschizontocidal antimalarial drug commonly prescribed for prevention of malaria in travelers. It is effective against the liver stage of the malaria parasite, which is crucial for preventing the development of the disease. Chingamin (A) is not a commonly used antimalarial drug. Biseptol (C) is a combination antibiotic and is not effective against malaria parasites. Quinine (D) is primarily used for treating malaria, not preventing it, and it is not specifically histoschizontocidal.

Correct Answer: C

Rationale: The correct answer is C: Intracellular parasitism. Genus Rickettsia representatives are known for their ability to live and replicate inside the host's cells, making them obligate intracellular parasites. This characteristic distinguishes them from other bacteria. A: Gram-positive cell wall is incorrect because Rickettsia have a gram-negative cell wall. B: High resistance to external environment factors is incorrect because Rickettsia are sensitive to environmental conditions and require specific host cells for survival. D: None of the above is incorrect because Rickettsia do exhibit the characteristic of intracellular parasitism.

Correct Answer: B

Rationale: The correct answer is B because there is no effective killed vaccine that is protective against all capsular types of Haemophilus spp. The Haemophilus influenzae vaccine primarily targets specific capsular types, not all of them. Choice A is incorrect because non-encapsulated strains can indeed be isolated from healthy carriers. Choice C is incorrect as Haemophilus influenzae is primarily transmitted through respiratory droplets, not through the air. Choice D is not correct because Choice B is indeed incorrect, making it the right answer.

Correct Answer: B

Rationale: Rationale: 1. The grain-like sediment indicates a precipitation reaction. 2. Precipitins are antibodies that cause precipitation reactions. 3. In serological diagnostics, precipitation reactions are used to detect specific antibodies. 4. Therefore, the reaction revealed in this scenario is due to the presence of precipitins. Summary: A: Bacteriolysins - These antibodies cause bacterial lysis, not precipitation. C: Antitoxins - These antibodies neutralize toxins, not involved in precipitation reactions. D: Opsonins - These antibodies enhance phagocytosis, not related to precipitation reactions.