A patient has been hospitalized with provisional diagnosis of botulism. What serological reaction should be used to reveal botulinum toxin?

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Microbiology Chapter 10 Test Bank Questions

Question 1 of 5

A patient has been hospitalized with provisional diagnosis of botulism. What serological reaction should be used to reveal botulinum toxin?

Correct Answer: A

Rationale: The correct answer is A: Neutralization reaction. This is the most appropriate serological test to reveal botulinum toxin because it involves mixing the patient's serum with known botulinum antitoxin. If the patient's serum contains botulinum toxin, it will neutralize the antitoxin, leading to a lack of toxin-neutralizing ability. The other choices are incorrect because agglutination reaction involves clumping of cells, not suitable for detecting botulinum toxin; Bordet-Gengou test is used to detect antibodies in pertussis infection, not botulinum toxin; and precipitation reaction involves the formation of a solid when two solutions are mixed, not ideal for detecting botulinum toxin.

Question 2 of 5

A man was admitted to the hospital on the 5th day of disease that manifested itself by jaundice, muscle aching, chill, nose bleedings. In course of laboratory diagnostics a bacteriologist performed darkfield microscopy of the patient's blood drop. Name a causative agent of this disease:

Correct Answer: A

Rationale: The correct answer is A: Leptospira interrogans. Darkfield microscopy is used to visualize spirochetes, which are spiral-shaped bacteria. Leptospira is a spirochete bacterium that causes leptospirosis, which presents with jaundice, muscle aching, chill, and nosebleeds. Leptospira is commonly transmitted through contact with contaminated water or soil. B: Borrelia dutlonii causes Lyme disease, which is transmitted by ticks and does not typically present with jaundice or nosebleeds. C: Calymmatobacterium granulomatis causes granuloma inguinale, a sexually transmitted infection that does not present with the symptoms described. D: Bartonella bacilloformis causes Carrion's disease, which presents with fever, anemia, and skin lesions but not jaundice or nosebleeds.

Question 3 of 5

A 30 y.o. patient is diagnosed with amebic dysentery. This diagnosis was bacteriologically confirmed. Name the preparation for its treatment:

Correct Answer: A

Rationale: The correct answer is A: Metronidazole. Amebic dysentery is caused by the parasite Entamoeba histolytica, not bacteria. Metronidazole is the drug of choice for treating this parasitic infection. It works by disrupting the DNA structure of the parasite, leading to its death. Mebendazole (B) is used to treat certain worm infections, not amebic dysentery. Itrakonazole (C) is an antifungal medication and not effective against parasites. Furacillin (D) is an antibacterial agent and not suitable for treating parasitic infections like amebic dysentery.

Question 4 of 5

A smear from frothy and purulent vaginal discharges of a 42 y.o. woman was stained by Romanovsky-Giemsa method. Its analysis revealed some microorganisms of flagellates class. What microorganism were the most probably revealed?

Correct Answer: A

Rationale: The correct answer is A: Trichomonas vaginalis. Trichomonas vaginalis is a flagellated protozoan that causes trichomoniasis, a sexually transmitted infection commonly found in vaginal discharges. In this case, the presence of flagellates in the vaginal discharge aligns with the characteristics of Trichomonas vaginalis. Leishmania donovani causes leishmaniasis, transmitted by sandflies. Trypanosoma gambiense causes African sleeping sickness through the tsetse fly bite. Trihomonas hominis is a non-pathogenic flagellate found in the human intestine. Therefore, the correct choice is A due to the correlation between the flagellates found in the vaginal discharge and the characteristics of Trichomonas vaginalis.

Question 5 of 5

Examination of a man revealed a protozoan disease that affected brain and caused vision loss. Blood analysis revealed unicellular half-moon-shaped organisms with pointed end. The causative agent of this disease is:

Correct Answer: A

Rationale: The correct answer is A: Toxoplasma. Toxoplasma gondii is a protozoan parasite that can infect the brain and cause vision loss. The description of half-moon-shaped organisms with a pointed end matches the appearance of Toxoplasma under the microscope. Toxoplasma is known to cause a condition called toxoplasmosis, which can lead to neurological symptoms such as vision loss. Leishmania, Lamblia, Amoeba, and Trichomonad are not known to cause brain infections or vision loss, making them incorrect choices.

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