ATI RN
Chemotherapy drugs Questions
Question 1 of 5
A patient develops antibiotic-associated pseudomembranous colitis (AAPMC) in response to drug therapy. Which of the following was the most likely cause of this severe problem?
Correct Answer: C
Rationale: Clindamycin is a common cause of C. difficile-associated pseudomembranous colitis.
Question 2 of 5
A sputum culture of a 65-year-old man with pneumonia is positive for Blactamase positive staphylococci. Which of the following is the best choice for penicillin therapy in this patient?
Correct Answer: C
Rationale: Oxacillin is effective against beta-lactamase-producing staphylococci.
Question 3 of 5
Which of the following statements is CORRECT?
Correct Answer: D
Rationale: Acute iron toxicity is managed with gastric lavage using bicarbonate to bind iron, reducing absorption. Hydroxocobalamin is not preferred for absorption speed but for cyanide poisoning; ferrous iron is better absorbed; ascorbic acid enhances iron absorption; dialysis patients often need folic acid.
Question 4 of 5
The following is NOT a characteristic feature of rivaroxiban compared to warfarin:
Correct Answer: D
Rationale: Rivaroxaban has a rapid onset, no INR monitoring, fewer CYP450 interactions, and a shorter duration (half-life ~5-9 hours) than warfarin, but it is not safe in severe renal impairment due to renal excretion, requiring dose adjustment.
Question 5 of 5
Which of the following is INCORRECT about cilostazol?
Correct Answer: B
Rationale: Cilostazol inhibits phosphodiesterase III, increasing cAMP (not breaking it down), leading to vasodilation and antiplatelet effects. It’s used for intermittent claudication, and headache is a common side effect.