ATI RN
Microbiology Chapter 12 Test Bank Questions
Question 1 of 9
A patient consulted a dentist about itching and burning in the oral cavity; high temperature. The patient was diagnosed with trichomonal gingivostomatitis. What drug should be chosen for his treatment?
Correct Answer: A
Rationale: Step 1: Trichomonal gingivostomatitis is caused by the parasite Trichomonas tenax. Step 2: Metronidazole is the drug of choice for treating infections caused by anaerobic organisms like Trichomonas. Step 3: Metronidazole effectively targets and eliminates Trichomonas parasites in the oral cavity. Step 4: Therefore, the correct drug choice for treating trichomonal gingivostomatitis is Metronidazole. Summary: - Ampicillin (B) is an antibiotic effective against Gram-positive bacteria, not parasites. - Gentamicin sulfate (C) is an antibiotic used for bacterial infections, not parasitic infections. - Nystatin (D) is an antifungal medication used for treating fungal infections, not parasitic infections like trichomonal gingivostomatitis.
Question 2 of 9
A 65-year-old patient with fever and a productive cough had a sputum sample revealing Gram-negative, non-motile, rod-shaped bacteria. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Klebsiella pneumoniae. This bacterium is commonly associated with pneumonia in elderly patients. Klebsiella pneumoniae is a Gram-negative, non-motile, rod-shaped bacterium that frequently causes pneumonia in individuals with underlying health conditions. It is known for its ability to produce a distinctive mucoid capsule. Pseudomonas aeruginosa (B) is more commonly associated with hospital-acquired infections, particularly in immunocompromised individuals. Escherichia coli (C) is a common cause of urinary tract infections but is less likely in this case due to the symptoms and sputum sample results. Haemophilus influenzae (D) is another common respiratory pathogen, but in this scenario, Klebsiella pneumoniae is the most likely causative agent based on the patient's age, symptoms, and the characteristics of the bacteria described in the sputum sample.
Question 3 of 9
Which of the following bacteria produce toxins that can cause severe gastrointestinal illness?
Correct Answer: D
Rationale: The correct answer is D, "All of the above," because all three bacteria listed (Vibrio cholerae, Clostridium difficile, Escherichia coli) produce toxins that can cause severe gastrointestinal illness. Vibrio cholerae produces cholera toxin leading to severe diarrhea. Clostridium difficile produces toxins causing antibiotic-associated diarrhea. Escherichia coli can produce toxins such as Shiga toxin causing severe gastrointestinal symptoms. Therefore, all the options listed are correct in producing toxins that can result in severe gastrointestinal illness.
Question 4 of 9
The tertiary stage of syphilis is usually manifested as:
Correct Answer: A
Rationale: The correct answer is A: Syphilitic granulomas (gummas). In the tertiary stage of syphilis, gummas, which are soft, tumor-like growths, can develop in various organs such as the skin, bones, liver, and brain. This stage typically occurs years after the initial infection and can lead to serious complications if left untreated. Purulent exudation from the urethra (B) is not specific to syphilis and may indicate other infections. Non-tender chancre (C) is characteristic of the primary stage of syphilis, not the tertiary stage. Diffuse maculopapular rash (D) is more commonly seen in the secondary stage of syphilis.
Question 5 of 9
Which bacteria are capable of producing an exotoxin that causes severe diarrhea?
Correct Answer: D
Rationale: The correct answer is D because all three bacteria listed are capable of producing exotoxins that can cause severe diarrhea. Escherichia coli can produce toxins that lead to diarrhea. Clostridium botulinum produces a neurotoxin causing botulism, which can also result in diarrhea. Vibrio cholerae is known for producing cholera toxin, a potent exotoxin that causes severe watery diarrhea. The other choices are incorrect because each bacterium listed is capable of producing a toxin that can cause diarrhea.
Question 6 of 9
The presence of flagella in bacterial cell represents:
Correct Answer: A
Rationale: The presence of flagella in a bacterial cell represents the H-antigen. Flagella are protein structures on the cell surface that play a role in bacterial motility. The H-antigen refers to the flagellar antigen, which is involved in immune responses and bacterial identification. Option A is correct because flagella are specifically associated with the H-antigen. Summarily, choices B and C are incorrect because the O-antigen and K-antigen are associated with lipopolysaccharide and capsule antigens, respectively, not flagella. Option D is incorrect as well because the correct association is with the H-antigen.
Question 7 of 9
Artificial active immunity occurs after a vaccination: injecting or taking antigens by mouth. Takes time for T and B cells to be activated but gives relatively long lasting:
Correct Answer: A
Rationale: 1. Vaccination introduces antigens to stimulate immune response. 2. T and B cells are activated to produce memory cells for long-lasting protection. 3. Active immunity develops over time post-vaccination. 4. Choice A is correct as it accurately describes the process and outcomes. 5. Choice B is incorrect as it contradicts the process of active immunity. 6. Choice C is incorrect as the process of active immunity is consistent regardless of the situation. 7. Therefore, the correct answer is A as it aligns with the mechanism and characteristics of artificial active immunity.
Question 8 of 9
A 10-year-old child had the mantoux tuberculin test administered. 48 hours later a papule up to 8 mm in diameter appeared on the site of the injection. What type of hypersensitivity reaction developed after the tuberculin injection?
Correct Answer: A
Rationale: The correct answer is A: Type IV hypersensitivity reaction. This type of reaction is characterized by a delayed response involving T cells. In this case, the appearance of a papule after 48 hours indicates a delayed hypersensitivity reaction, which is typical of a Type IV reaction. The other choices are incorrect because: B: Arthus phenomenon is a localized immune complex-mediated reaction, not seen in tuberculin tests. C: Seroreaction typically involves antibodies reacting with soluble antigens, not seen in this scenario. D: Type II hypersensitivity reactions involve antibodies targeting specific cells or tissues, which is not the mechanism at play in this case.
Question 9 of 9
A 33 year old patient was delivered to the infectious diseases department on the 7-th day of disease. He complained about great weakness, high temperature, pain in the lumbar area and leg muscles, icteritiousness, dark color of urine, headache. The acute disease started with chill, body temperature rise up to 40oC, headache, pain in the lumbar area and sural muscles. Icterus turned up on the 4th day, nasal and scleral haemorrhages came on the 5th day. Fever has lasted for 6 days. Diuresis - 200 ml. What is the most probable diagnosis?
Correct Answer: A
Rationale: The most probable diagnosis is Leptospirosis. The symptoms described align with the classic presentation of Leptospirosis, such as fever, muscle pain, headache, jaundice, and hemorrhages. The initial symptoms of chills, high fever, and muscle pain followed by jaundice and hemorrhages are characteristic of Leptospirosis. The presence of dark urine and low diuresis also point towards kidney involvement, which is common in Leptospirosis due to renal failure. Additionally, the patient's history of potential exposure to contaminated water or soil supports the diagnosis, as Leptospirosis is commonly transmitted through contact with infected animal urine. Summary of other choices: - Typhoid fever typically presents with sustained fever, abdominal pain, and constipation, not matching the symptoms described. - Virus A hepatitis usually presents with jaundice, but other symptoms such as muscle pain and hemorrhages are not typical. - Sepsis is a systemic response