ATI RN
Microbiology A Systems Approach Test Bank Questions
Question 1 of 9
A patient complains of acute spastic abdominal pain, frequent urge to defecate, liquid bloody feces with mucus. Laboratory analysis of fecal smear revealed inconstant in shape organisms with erythrocyte. What is the most likely diagnosis?
Correct Answer: A
Rationale: The correct answer is A: Amebiasis. Amebiasis is caused by the parasite Entamoeba histolytica, presenting with symptoms like acute abdominal pain, bloody diarrhea with mucus, and inconstant shape organisms seen in fecal smear. The presence of erythrocytes supports the diagnosis due to the parasite's ability to invade intestinal mucosa causing bleeding. Choice B (Lambliasis) presents with different symptoms like steatorrhea and fatigue. Choice C (Schistosomiasis) is mainly associated with liver and urinary symptoms. Choice D (Intestinal trichomoniasis) commonly presents with watery diarrhea and does not typically cause bloody stools. Therefore, based on the patient's symptoms and fecal smear findings, Amebiasis is the most likely diagnosis.
Question 2 of 9
After starting treatment for pulmonary tuberculosis a patient complained about red tears and urine. What drug could cause such changes?
Correct Answer: A
Rationale: The correct answer is A: Rifampicin. Rifampicin is known to cause red discoloration of bodily fluids, including tears and urine, due to its side effect of harmless color changes. Benzylpenicillins (B and C) and Biseptol-480 do not typically cause such discoloration. Rifampicin's mechanism of action involves binding to bacterial RNA polymerase, leading to inhibition of RNA synthesis, which is unrelated to the mechanism of the other drugs. Thus, based on the unique side effect profile of Rifampicin and its mechanism of action, it is the most likely drug causing red tears and urine in this scenario.
Question 3 of 9
A bacteriological laboratory has been investigating a sample of homemade dried fish that was the cause of severe food poisoning. Microscopy of the culture inoculated in Kitt-Tarozzi medium revealed microorganisms resembling a tennis racket. What diagnosis can be made?
Correct Answer: A
Rationale: The correct answer is A: Botulism. The tennis racket appearance seen under the microscope is characteristic of Clostridium botulinum, the bacterium responsible for botulism. This bacterium produces spores that resemble a tennis racket shape. Botulism is a type of food poisoning caused by the ingestion of the toxin produced by Clostridium botulinum. Summary: B: Salmonellosis is caused by Salmonella bacteria, which do not exhibit a tennis racket appearance. C: Cholera is caused by Vibrio cholerae, which also does not resemble a tennis racket under the microscope. D: Dysentery is typically caused by bacteria such as Shigella or Entamoeba histolytica, neither of which exhibit the characteristic tennis racket appearance.
Question 4 of 9
During the staining of sputum smear of a patient with suspected croupous pneumonia the following reactives and stainers were used: gentian violet solution, Lugol's solution, 960 spiritus and water fuchsin. What method of staining is used in this case?
Correct Answer: B
Rationale: The correct answer is B: Gram's staining method. The rationale for this is as follows: Gentian violet and Lugol's solution are used as primary and mordant stains in the Gram's staining method. Spiritus 960 is used as a decolorizer, and water fuchsin is used as a counterstain. This staining method is commonly used in microbiology to differentiate bacteria into Gram-positive and Gram-negative based on their cell wall characteristics. A: Leffler's staining method is used for the identification of diphtheria bacilli. C: Ziehl-Neelsen's staining method is used for acid-fast bacteria like Mycobacterium tuberculosis. D: Neisser's staining method is used for the identification of Neisseria species. In summary, the use of specific reactives and stainers in the question indicates the application of the Gram's staining method for bacterial differentiation.
Question 5 of 9
A patient with a severe sore throat had a throat culture revealing Gram-positive cocci in chains. The bacteria were beta-hemolytic. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Streptococcus pyogenes. This bacterium is the most likely causative agent due to its characteristic features. Streptococcus pyogenes is Gram-positive cocci in chains, which matches the description provided in the question. It is also known to be beta-hemolytic, causing complete lysis of red blood cells on blood agar. Streptococcus pyogenes is a common pathogen causing sore throat, often associated with pharyngitis. Explanation for incorrect choices: B: Streptococcus pneumoniae - This bacterium is Gram-positive but usually occurs in pairs (diplococci) and is alpha-hemolytic. C: Enterococcus faecalis - This bacterium is Gram-positive cocci but is not typically beta-hemolytic and is not commonly associated with sore throat infections. D: Staphylococcus aureus - This bacterium is Gram-positive cocci but usually occurs in clusters and
Question 6 of 9
What type of bacteria is responsible for causing tuberculosis?
Correct Answer: A
Rationale: The correct answer is A: Mycobacterium tuberculosis. This bacterium is responsible for causing tuberculosis, as it has unique characteristics that allow it to infect the lungs and evade the immune system, leading to a chronic infection. Mycobacterium tuberculosis is a slow-growing, acid-fast bacterium that can survive and replicate within macrophages, causing the characteristic granulomas seen in tuberculosis. Choice B, Escherichia coli, is a common gut bacterium and is not responsible for tuberculosis. Choice C, Clostridium botulinum, causes botulism, not tuberculosis. Choice D, Salmonella enterica, causes food poisoning, not tuberculosis.
Question 7 of 9
The effect of which of the following toxins DOES NOT MANIFEST with neurological symptoms:
Correct Answer: D
Rationale: Certainly! The correct answer is D: Pertussis exotoxin. Pertussis toxin primarily affects the respiratory system causing whooping cough. It does not directly target the nervous system like the other toxins listed. Tetanospasmin causes muscle spasms, Diphtheria exotoxin affects the heart and nerves, and Botulinum exotoxin causes paralysis by blocking neurotransmitter release. Therefore, Pertussis exotoxin is the only toxin among the options that does not manifest with neurological symptoms.
Question 8 of 9
Bacterial infections of the female reproductive system include:
Correct Answer: A
Rationale: Rationale: 1. Vaginitis is a common bacterial infection in the female reproductive system. 2. Toxic shock syndrome can be caused by certain bacterial infections. 3. Endometritis is inflammation of the endometrium often due to bacterial infections. 4. Salpingitis is inflammation of the fallopian tubes, commonly caused by bacteria. Summary: - Choice B: Nephritis is a kidney infection, not related to female reproductive system infections. - Choice C: Nephritis and cystitis are not specific to the female reproductive system. - Choice D: Cystitis is a bladder infection, not typically considered part of female reproductive system infections.
Question 9 of 9
Peptidoglycan is typically found in the:
Correct Answer: A
Rationale: Peptidoglycan is a major component of bacterial cell walls, providing structural support and protection. The correct answer is A because peptidoglycan is typically found in the cell wall of bacteria. The cell wall is crucial for maintaining the shape of the bacterial cell and protecting it from external stresses. The plasma membrane (choice B) is primarily composed of phospholipids and proteins, not peptidoglycan. The nucleus (choice C) is found in eukaryotic cells and contains genetic material, not peptidoglycan. The endoplasmic reticulum (choice D) is an organelle involved in protein synthesis and lipid metabolism, but it does not contain peptidoglycan. Therefore, the correct answer is A as peptidoglycan is typically found in the cell wall of bacteria.