ATI RN
ATI RN Pharmacology Online Practice 2023 A Questions
Question 1 of 5
A patient calls the clinic office saying that the cholestyramine (Questran) powder he started yesterday clumps and sticks to the glass when he tries to mix it. The nurse will suggest what method for mixing this medication for administration?
Correct Answer: C
Rationale: The nurse should suggest the patient mix the cholestyramine powder with food or fruit, or at least 4 to 6 ounces of fluid. Cholestyramine is a medication that works by binding with bile acids in the intestine, which requires mixing the powder with a sufficient amount of fluid to ensure proper administration. Mixing the powder with 4 to 6 ounces of fluid or food will help prevent clumping and ensure optimal effectiveness of the medication. Mixing it with a carbonated soda drink (option A) may not be ideal as the effervescence could affect the medication's stability. Adding the powder to any liquid and stirring vigorously (option B) may not effectively dissolve the powder. Taking the powder dry followed by a glass of water (option E) may also not be as effective in ensuring proper administration as when mixed with food or fluid.
Question 2 of 5
The nurse administers IV mannitol to a client with cerebral edema. Which parameter should the nurse monitor closely?
Correct Answer: A
Rationale: Mannitol, an osmotic diuretic, reduces cerebral edema by drawing fluid into the vasculature, excreted via urine. Monitoring urine output ensures efficacy and prevents fluid overload or renal strain, critical in brain injury. BP and pupils matter but follow diuresis. Temperature is unrelated. Urine output aligns with mannitol's action, key in cerebral edema where ICP reduction hinges on fluid shift, making A the priority parameter.
Question 3 of 5
Dr. Smith orders a gram of human salt poor albumin product for a patient. The product is available in a 50-milliliter vial with a concentration of 25 percent. What dosage will the nurse administer?
Correct Answer: A
Rationale: To calculate the dosage of human salt poor albumin product that the nurse will administer, we need to determine the volume of product containing 1 gram of albumin.
Question 4 of 5
A patient receiving erythropoietin-stimulating drug has the following laboratory values: hemoglobin, 12.8 mg/dL; platelet count, 148,000/mm2; white blood cell count, 4800/mm2. Which action is most appropriate for the nurse to implement?
Correct Answer: B
Rationale: The patient's hemoglobin level of 12.8 mg/dL is within the target range for erythropoietin therapy, which is typically 10-12 g/dL. The nurse should continue monitoring the patient and ensure that the hemoglobin does not exceed 12 g/dL, as higher levels can increase the risk of thromboembolic events. Administering additional erythropoietin is unnecessary and potentially harmful. Stopping the medication abruptly is not indicated unless directed by the healthcare provider. Colony-stimulating factors are used to increase white blood cell counts, not hemoglobin levels.
Question 5 of 5
Which drug in the following list has an analgesic effect which is not mediated wholly or partly by binding to opioid receptors?
Correct Answer: D
Rationale: Analgesics often act via opioid receptors. Codeine, a weak mu-opioid agonist, relieves mild pain. Tramadol combines mu agonism with serotonin/norepinephrine reuptake inhibition. Dextropropoxyphene is a mu agonist, buprenorphine a partial agonist. Nefopam's analgesia involves monoamine reuptake inhibition and possibly NMDA antagonism, not opioid receptors, distinguishing it. This non-opioid mechanism suits patients intolerant to opioids, offering an alternative in pain management.