Correct Answer: A

Rationale: The correct answer is A: Streptomycin. Streptomycin is an aminoglycoside antibiotic used to treat tuberculosis that can cause hearing loss as a side effect. It is known to damage the cochlear and vestibular organs in the inner ear. The other choices, B: Isoniazid, C: Rifampicin, and D: Ethionamide, are not associated with causing hearing deterioration as a side effect. Isoniazid can rarely cause peripheral neuropathy, Rifampicin can lead to hepatotoxicity, and Ethionamide may cause gastrointestinal disturbances, but none of these drugs are known to specifically cause hearing loss.

Correct Answer: A

Rationale: Subcutaneous mycoses are fungal infections that affect the skin, subcutaneous tissues, and bones. The correct answer is A: tropics, as these infections are more commonly found in warm and humid regions. Fungi that cause subcutaneous mycoses thrive in tropical climates due to the favorable conditions for their growth and transmission. Choices B, C, and D are incorrect because deserts (B) have dry conditions not conducive to fungal growth, forests of the Northern Hemisphere (C) have varying climates that may not support the specific fungi causing subcutaneous mycoses, and the Rocky Mountains (D) are not typically associated with the high humidity required for these infections.

Correct Answer: A

Rationale: The correct answer is A: Escherichia coli. E. coli is a Gram-negative rod that ferments lactose, leading to red colonies on Endo agar. This bacterium is commonly found in the human gut and is known for its ability to ferment lactose. Salmonella and Shigella are also Gram-negative rods but do not ferment lactose, so they would not produce red colonies on Endo agar. Proteus is a Gram-negative rod that is not known for its lactose-fermenting ability and would not produce red colonies on Endo agar. Therefore, based on the characteristics provided, E. coli is the most likely microorganism responsible for the red colonies on Endo agar.

Correct Answer: A

Rationale: The correct answer is A: Staphylococcus epidermidis. 1. Gram-positive cocci suggest a staphylococcal species. 2. Catalase-positive indicates it belongs to the Staphylococcus genus. 3. Coagulase-negative rules out Staphylococcus aureus. 4. Staphylococcus epidermidis is a common cause of infections in immunocompromised patients. Summary: - B: Staphylococcus aureus is coagulase-positive. - C: Streptococcus pneumoniae is a Gram-positive diplococci. - D: Neisseria meningitidis is a Gram-negative diplococci.

Correct Answer: C

Rationale: The correct answer is C: Quinine. Quinine is known for its destructive effect on erythrocytic forms of malarial plasmodia and dysenteric amoebae. It is commonly used for the treatment and prevention of diseases such as malaria, amebiasis, and interstitial disease. Quinine works by interfering with the parasite's ability to break down hemoglobin in red blood cells, ultimately leading to their destruction. Incorrect choices: A: Chingamin - Chingamin is not typically used to treat malaria, amebiasis, or interstitial disease. B: Emetine hydrochloride - Emetine hydrochloride is primarily used for treating amoebic dysentery and is not commonly used for malaria treatment. D: Erythromycin - Erythromycin is an antibiotic used to treat bacterial infections, not parasitic infections like malaria or amebiasis.