A patient being treated for tuberculosis is suffering from hearing deterioration. What drug causes this complication?

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Microbiology An Introduction 12th Edition Test Bank Questions

Question 1 of 9

A patient being treated for tuberculosis is suffering from hearing deterioration. What drug causes this complication?

Correct Answer: A

Rationale: The correct answer is A: Streptomycin. Streptomycin is an aminoglycoside antibiotic used to treat tuberculosis that can cause hearing loss as a side effect. It is known to damage the cochlear and vestibular organs in the inner ear. The other choices, B: Isoniazid, C: Rifampicin, and D: Ethionamide, are not associated with causing hearing deterioration as a side effect. Isoniazid can rarely cause peripheral neuropathy, Rifampicin can lead to hepatotoxicity, and Ethionamide may cause gastrointestinal disturbances, but none of these drugs are known to specifically cause hearing loss.

Question 2 of 9

During the examination of a patient, who had been to the mountain pasture and had been hospitalized in a bad condition with fever, the doctor found out the enlargement of inguinal lymph nodes to 8 cm, which were attached to the surrounding tissues, immovable, the skin above them was red and tender. The microscopic examination of the node revealed acute serohemorrhagic inflammation. What disease is it typical for?

Correct Answer: B

Rationale: Rationale: 1. The patient has symptoms of fever, enlarged lymph nodes, red and tender skin, which are indicative of systemic infection. 2. The inguinal lymph nodes in plague become enlarged, tender, and painful, forming buboes. 3. The presence of acute serohemorrhagic inflammation in the lymph node is characteristic of plague. 4. Plague is a zoonotic bacterial infection caused by Yersinia pestis, commonly transmitted through fleas from rodents. 5. Brucellosis, anthrax, and tularemia do not typically present with inguinal lymph node involvement and acute serohemorrhagic inflammation. Summary: - Brucellosis: Usually presents with flu-like symptoms, joint pain, and fever, not inguinal lymph node enlargement. - Anthrax: Presents with skin lesions, respiratory symptoms, or gastrointestinal symptoms, not inguinal lymph node involvement. - Tularemia: Presents with fever, skin ulcers,

Question 3 of 9

A stool sample from a patient with chronic diarrhea revealed cysts with four nuclei. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Entamoeba histolytica. This is because it is a protozoan parasite known to cause amoebic dysentery, presenting with chronic diarrhea and cysts with four nuclei in the stool sample. Giardia lamblia (B) causes giardiasis with trophozoites and cysts with two nuclei. Balantidium coli (C) is a ciliated parasite causing dysentery with large trophozoites. Trichomonas hominis (D) is a non-pathogenic flagellate often found in the human intestine. Thus, based on the specific characteristics of the cysts and clinical presentation, Entamoeba histolytica is the most likely causative agent.

Question 4 of 9

A bacteriological laboratory has received smears from the sputum of a patient with a chronic pulmonary disease. Microscopical examination of the smears stained by the Ziehl-Neelsen technique revealed red bacilli. What property of the tuberculosis bacillus has shown itself?

Correct Answer: A

Rationale: The correct answer is A: Acid resistance. The Ziehl-Neelsen staining technique is specifically used to detect acid-fast bacteria like Mycobacterium tuberculosis, which is resistant to acid decolorization. This property allows the tuberculosis bacillus to retain the stain even after exposure to acid-alcohol, appearing red under the microscope. Explanation of incorrect choices: B: Alkali resistance - This property is not relevant in the context of Ziehl-Neelsen staining for acid-fast bacteria. C: Alcohol resistance - While alcohol resistance is related to acid-fastness, it is not the specific property highlighted by Ziehl-Neelsen staining. D: Capsule formation - Capsule formation is a different characteristic and not directly related to the staining behavior of acid-fast bacteria in the Ziehl-Neelsen technique.

Question 5 of 9

Which bacteria are capable of producing exotoxins?

Correct Answer: D

Rationale: The correct answer is D: All of the above. Clostridium tetani, Staphylococcus aureus, and Escherichia coli are all capable of producing exotoxins. Exotoxins are proteins released by bacteria that can cause damage to the host. Clostridium tetani produces tetanospasmin, causing tetanus. Staphylococcus aureus produces toxins like enterotoxin and toxic shock syndrome toxin-1. Escherichia coli can produce Shiga toxin and heat-labile toxin. Therefore, all three bacteria listed can produce exotoxins, making choice D the correct answer. Choices A, B, and C are incorrect as they do not encompass all the bacteria capable of producing exotoxins.

Question 6 of 9

Sterilization destroys all microorganisms including:

Correct Answer: C

Rationale: Sterilization refers to the complete elimination of all microorganisms, including their spores, which are the most resistant form of microbial life. Spores have a tough outer coating that protects them from harsh conditions, making them more difficult to destroy compared to vegetative cells, viruses, and protozoa. Therefore, the correct answer is C because sterilization targets and eliminates all forms of microorganisms, including spores. Choices A, B, and D are incorrect because sterilization goes beyond just targeting vegetative cells, viruses, or protozoa; it aims to eliminate all microorganisms present.

Question 7 of 9

Which bacteria are capable of producing spores that can survive extreme environmental conditions?

Correct Answer: C

Rationale: The correct answer is C (Both A and B) because both Clostridium botulinum and Bacillus anthracis are capable of producing spores. Spores are highly resistant structures that allow bacteria to survive harsh environmental conditions. Clostridium botulinum and Bacillus anthracis produce spores as a survival mechanism when conditions become unfavorable. Choice A (Clostridium botulinum) is incorrect because it only represents one of the bacteria capable of producing spores. Choice B (Bacillus anthracis) is also incorrect as it alone does not encompass all bacteria capable of producing spores. Choice D (None of the above) is incorrect as both bacteria mentioned can produce spores.

Question 8 of 9

The complex of all biological processes/mechanisms responsible for the state of steady internal, physical and chemical conditions in the living systems and defense against all foreign agents is knows as:

Correct Answer: B

Rationale: The correct answer is B: homeostasis. Homeostasis refers to the process by which living organisms maintain a stable internal environment despite external changes. It involves various biological processes and mechanisms that regulate factors such as temperature, pH, and nutrient levels within narrow limits. This is crucial for the proper functioning of cells, tissues, and organs. Now, let's analyze the other choices: A: Infection - Infection refers to the invasion and multiplication of harmful microorganisms in the body, leading to illnesses. It is not the correct answer as it does not encompass the overall maintenance of internal conditions. C: Immunity - Immunity is the body's ability to resist and fight off infections. While immunity is related to defense against foreign agents, it does not fully capture the concept of maintaining internal stability. D: Commensalism - Commensalism is a type of symbiotic relationship between different species where one benefits without harming the other. It is not related to the overall regulation of

Question 9 of 9

A child with fever and swollen lymph nodes had a Gram-stained smear revealing Gram-negative rods with a safety pin appearance. What is the causative agent?

Correct Answer: A

Rationale: The correct answer is A: Yersinia pestis. This bacterium causes the plague, which presents with fever and swollen lymph nodes. The safety pin appearance on Gram stain is characteristic of Yersinia pestis. B: Francisella tularensis causes tularemia, which presents differently and does not show safety pin appearance on Gram stain. C: Brucella abortus causes brucellosis, which does not typically present with the same symptoms as described in the question. D: Clostridium botulinum causes botulism, which does not show safety pin appearance on Gram stain and does not typically present with fever and swollen lymph nodes.

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