A patient asks you how does the statin drugs work. How would you respond?

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ATI Pharmacology Across the Lifespan Questions

Question 1 of 5

A patient asks you how does the statin drugs work. How would you respond?

Correct Answer: B

Rationale: The correct answer is B: It inhibits hydroxymethyl lutaryl-coenzyme A (HMG-CoA) reductase to reduce the biosynthesis of cholesterol in the liver. Statin drugs work by blocking the enzyme HMG-CoA reductase, which is involved in the synthesis of cholesterol in the liver. By inhibiting this enzyme, statins reduce the production of cholesterol in the body. This mechanism helps lower the levels of LDL (bad) cholesterol in the blood. Incorrect choices: A: It inhibits the absorption of dietary cholesterol in the small intestine - This is incorrect because statins do not affect the absorption of dietary cholesterol but rather target cholesterol synthesis in the liver. C: It binds to bile in the intestinal track forming an insoluble complex that is excreted in the feces - This is incorrect as it describes the mechanism of bile acid sequestrants, not statins. D: It stimulates the biliary system to increase the excretion of

Question 2 of 5

A patient who previously reported feeling better on the current drug regimen suddenly reports that the drug seems to have stopped working. This is known as:

Correct Answer: A

Rationale: The correct answer is A: Tachyphylaxis. Tachyphylaxis refers to a rapid decrease in response to a drug after repeated administration. In this case, the patient initially felt better on the drug regimen but now feels it has stopped working, indicating a sudden loss of effectiveness. Incorrect Choices: B: Side effect - Side effects are unintended, secondary effects of a drug that can occur at therapeutic doses, not related to a sudden loss of efficacy. C: Adverse effect - Adverse effects are harmful or undesired effects that may occur with a drug but do not necessarily mean the drug has stopped working. D: Tolerance - Tolerance is a gradual decrease in response to a drug with repeated use, not a sudden loss of effectiveness as described in the scenario.

Question 3 of 5

Which statement by a patient about the use of aspirin during pregnancy indicates a need for further learning?

Correct Answer: B

Rationale: Correct Answer: B Rationale: 1. Aspirin is not recommended for pain relief during pregnancy due to potential risks to the fetus. 2. Choice A is incorrect as aspirin can affect hemostasis in the newborn. 3. Choice C is incorrect as aspirin can cause antepartum hemorrhage. 4. Choice D is incorrect as aspirin is most harmful when used early in pregnancy, not late.

Question 4 of 5

Which of the follow is not one of the four processes of pharmacokinetics?

Correct Answer: A

Rationale: The correct answer is A: Administration. Pharmacokinetics involves the processes of Absorption, Distribution, Metabolism, and Excretion (ADME). Administration refers to the act of giving a drug to a patient, which is not a process that occurs within the body. Absorption involves the movement of the drug into the bloodstream, Distribution is the movement of the drug throughout the body, and Excretion is the removal of the drug from the body. Therefore, Administration is not one of the four processes of pharmacokinetics.

Question 5 of 5

The patient asks if there is any other option besides antibiotics to treat acute otitis media. How will you respond?

Correct Answer: D

Rationale: The correct answer is D because pain management is an essential part of treating acute otitis media, along with antibiotics if necessary. Step 1: Addressing pain helps improve the patient's comfort and quality of life. Step 2: Pain management can include over-the-counter pain relievers or ear drops. Step 3: Antibiotics are not always needed, especially in mild cases or when the infection is viral. Summary: Option A is incorrect as pain management is beneficial regardless of antibiotics. Option B is incorrect as antibiotics are not always the sole treatment. Option C is incorrect as pain management can be used even without a burst tympanic membrane.

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