A patient arrives in the emergency department with severe chest pain. The patient reports that the pain has been occurring off and on for a week now. Which assessment finding would indicate the need for cautious use of nitrates and nitrites?

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ATI Intro to Pharmacology Quizlet Questions

Question 1 of 5

A patient arrives in the emergency department with severe chest pain. The patient reports that the pain has been occurring off and on for a week now. Which assessment finding would indicate the need for cautious use of nitrates and nitrites?

Correct Answer: A

Rationale: A patient arriving in the emergency department with severe chest pain and a history of episodic chest pain over the past week may be experiencing a myocardial infarction or other serious cardiac event. Nitrates and nitrites are commonly used to manage chest pain in such situations because they help dilate blood vessels, improve blood flow to the heart, and reduce the workload on the heart.

Question 2 of 5

A side e昀昀ect given o昀昀 by omeprazole is:

Correct Answer: B

Rationale: Omeprazole is a proton pump inhibitor commonly used to reduce stomach acid production. One of the side effects of omeprazole is a change in stomach pH. By inhibiting the proton pumps in the stomach lining, omeprazole reduces the production of acid, leading to an increase in the pH level of the stomach. This change in stomach pH can affect the overall balance of acidity in the stomach and may result in various gastrointestinal symptoms such as bloating, gas, or changes in digestion. It is important for individuals taking omeprazole to be aware of this potential side effect and consult their healthcare provider if they experience any unusual symptoms.

Question 3 of 5

The nurse administers atenolol (Tenormin) to a client with hypertension. Which finding would prompt the nurse to hold the dose and notify the physician?

Correct Answer: B

Rationale: Atenolol, a beta-blocker, lowers blood pressure and heart rate by blocking sympathetic stimulation. A heart rate of 52 bpm is bradycardic (below 60 bpm), a threshold for holding beta-blockers due to risk of inadequate perfusion, especially in hypertension where cardiac output matters. Holding and notifying the physician prevents harm, allowing reassessment. BP of 130/80 is controlled, not urgent. Respiratory rate of 18 and temperature of 98.6°F are normal. Atenolol's selectivity for beta-1 receptors makes bradycardia a key adverse effect, requiring vigilance. This action aligns with nursing protocols for beta-blockers, prioritizing cardiovascular stability, making B the finding warranting immediate intervention.

Question 4 of 5

At a dose of 10 mg, drug X lowers total cholesterol by 50 mg/dL, while a maximum drop in cholesterol of 65 mg/dL is achieved at 40 mg. At a dose of 5 mg, drug Y lowers cholesterol by 50 mg/dL, while a maximum drop in cholesterol of 55 mg/dL is achieved at 10 mg. What can be concluded about the efficacy and potency of these two drugs?

Correct Answer: D

Rationale: Potency is dose for effect-Drug Y lowers 50 mg/dL at 5 mg, versus X at 10 mg, making Y more potent. Efficacy is max effect-X's 65 mg/dL beats Y's 55 mg/dL, giving X higher efficacy. X isn't more potent-higher dose needed. Y's potency and X's efficacy align with data, per pharmacodynamics.

Question 5 of 5

If you are treating a patient that has renal failure, what type of pain medications should you avoid?

Correct Answer: B

Rationale: In patients with renal failure, NSAIDs (Nonsteroidal anti-inflammatory drugs) should be avoided as they can further impair kidney function and potentially cause kidney damage. NSAIDs can lead to acute kidney injury and worsen existing renal conditions by affecting prostaglandin synthesis in the kidneys, leading to decreased renal blood flow. It is essential to choose pain medications that do not rely on the kidneys for metabolism or excretion, such as nonopioid analgesics or certain types of opioids that are safe for use in renal impairment. It is advisable to consult with a healthcare provider for proper pain management in patients with renal failure.

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