A painless nodule in the thyroid or in the neck is the usual presentation of childhood thyroid cancer. Of the following, the MOST common site of distant metastasis is

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Endocrine System Pediatrics Questions

Question 1 of 5

A painless nodule in the thyroid or in the neck is the usual presentation of childhood thyroid cancer. Of the following, the MOST common site of distant metastasis is

Correct Answer: D

Rationale: Lungs (E) are the most common site of distant metastasis in pediatric thyroid cancer.

Question 2 of 5

Patients with mineralocorticoid deficiency can develop the following EXCEPT

Correct Answer: C

Rationale: Mineralocorticoid deficiency causes metabolic acidosis, not alkalosis (C), due to sodium loss and hydrogen retention.

Question 3 of 5

Classic 21-hydroxylase deficiency occurs in approximately 1 in 15,000-20,000 births in most populations. Of affected infants, the salt-losing form constitute about

Correct Answer: D

Rationale: About 70% (D) of 21-hydroxylase deficiency cases are salt-losing.

Question 4 of 5

In primary aldosteronism, one of the following is low

Correct Answer: B

Rationale: Primary aldosteronism causes metabolic alkalosis, lowering serum CO₂ (B) due to HCO₃ retention.

Question 5 of 5

Klinefelter syndrome is the most common sex chromosomal aneuploidy in males, all the following features are true EXCEPT

Correct Answer: D

Rationale: Many with Klinefelter syndrome (47,XXY) complete high school (not few, D); other features are accurate.

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