A nurse is teaching the client with systemic lupus erythematosus about prednisone. What information is the priority?

Correct Answer: D

Rationale: The correct answer is D because abruptly stopping prednisone can lead to adrenal insufficiency due to suppression of the body's natural cortisol production. Adrenal insufficiency can be life-threatening. Priority is given to this information to ensure the client's safety. Choice A is incorrect as jitteriness or nervousness are common side effects but not the priority. Choice B is incorrect as sodium and fluid retention are potential side effects but not as critical as avoiding adrenal insufficiency. Choice C is incorrect as fat redistribution is a long-term effect but not as immediate as the risk of adrenal insufficiency.

Correct Answer: E

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: The correct answer is A: Sex bias observed with males more at risk of developing the disease. This statement is NOT true because MS actually has a sex bias towards females, with women being more at risk. This is due to hormonal, genetic, and immunological factors. The other choices are true: B is correct as MS is more common in northern regions, possibly due to environmental factors; C is correct since MS is characterized by demyelination of neurons leading to various symptoms; and D is correct as experimental autoimmune encephalomyelitis (EAE) is an animal model often used to study MS, induced by injecting myelin components to trigger an immune response.

Correct Answer: D

Rationale: The correct answer is D because a strong cytotoxic T cell response can still effectively clear the virus even without neutralizing antibodies. Cytotoxic T cells directly kill infected cells, helping to control and eliminate the virus. Therefore, the vaccine would not result in failure to clear the virus. A) Incorrect: While the vaccine may not prevent infection, the presence of cytotoxic T cells would help in controlling and reducing the severity of the infection. B) Incorrect: The vaccine may indeed lessen the severity of the disease by aiding in the clearance of infected cells. C) Incorrect: A strong T cell response can provide broader protection against different variants of the virus.

Correct Answer: B

Rationale: The correct answer is B because upregulation of endothelial adhesion molecules is the first event during an acute inflammatory response. This event facilitates the initial recruitment of leukocytes, including neutrophils, to the site of inflammation. Extravasation of neutrophils (choice A) occurs after adhesion molecules are upregulated. Secretion of opsonins (choice C) and phagocytosis (choice D) occur later in the inflammatory response process after the neutrophils have been recruited to the site of inflammation.