ATI RN
RN ATI Capstone Pharmacology 2 Quiz Questions
Question 1 of 5
A nurse is instructing a client regarding carbidopa-levodopa (Sinemet) for the treatment of Parkinson’s disease. The nurse tells the client which of the following indicates an overdose of the medication?
Correct Answer: A
Rationale: An overdose of carbidopa-levodopa (Sinemet) can cause excessive dopaminergic stimulation, leading to dyskinesias or difficulty performing voluntary movements. Increased blood pressure, decreased appetite, and black tarry stools are not typical signs of overdose. Therefore, difficulty with voluntary movement is the correct indicator of overdose.
Question 2 of 5
Trimethoprim:
Correct Answer: B
Rationale: Trimethoprim inhibits dihydrofolate reductase, not activates it, blocking folate synthesis in bacteria, so that's false. It's a weak base, a true statement, aiding its concentration in acidic environments like urine. It has good prostate penetration, effective in prostatitis, making that false. It distributes into CSF, useful in meningitis, so that's incorrect. It's teratogenic, not harmless in pregnancy. Its basic nature enhances its antibacterial efficacy, a key pharmacokinetic advantage in urinary tract infections.
Question 3 of 5
During pharmacology class, the student nurse asks the nursing instructor how students will ever learn about the individual antibiotic drugs since there are so many. What is the best response by the nursing instructor?
Correct Answer: D
Rationale: Learning a representative (prototype) drug from each antibiotic class simplifies understanding by focusing on shared traits-mechanisms, effects, and side effects-reducing the burden of memorizing every drug. Mnemonics aid recall but don't teach concepts. Flow charts organize but lack depth. Categorizing is broad, while prototypes offer a practical, foundational approach, widely used in pharmacology education for mastery.
Question 4 of 5
When reading about a drug, the nurse learns it has a median toxic dose of 50 mg. The patient has been receiving 60 mg of the drug. What analysis does the nurse make?
Correct Answer: C
Rationale: Median toxic dose (TD50) is where 50% show toxicity-60 mg exceeds this, raising adverse effect risk (e.g., toxicity signs), not lethality for all. Effect may persist, not fail. Efficacy/potency are defined, just exceeded. Lethal dose (LD50) differs-60 mg isn't half lethal. Excess drives risk, per pharmacodynamics.
Question 5 of 5
The patient receives imipramine (Tofranil) as treatment for depression. He is admitted to the emergency department following an intentional overdose of this medication. What will the priority assessment by the nurse include?
Correct Answer: A
Rationale: Imipramine, a TCA, in overdose risks cardiac toxicity-arrhythmias (e.g., QRS widening)-per toxicology, making heart status priority. Liver and renal function matter but are secondary-cardiac collapse kills faster. Neurological signs (e.g., seizures) follow but heart trumps. Cardiac focus saves lives, per protocol.