A novel medication to treat gastric motility disorders will act at the terminal step in the synthesis/breakdown of acetylcholine. Which of the following is the terminal step in the synthesis and release of acetylcholine?

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Pharmacology CNS Drugs Classification Questions

Question 1 of 5

A novel medication to treat gastric motility disorders will act at the terminal step in the synthesis/breakdown of acetylcholine. Which of the following is the terminal step in the synthesis and release of acetylcholine?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

An 8-year-old boy presents to the emergency department after seizure-like activity. During class, the teacher noted that the boy stare off for about 45 s. He has done this three times in the past. He would not respond to her during the episode and was confused for about 1 min following it. What is the most appropriate first-line therapy for this child?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

A 42-year-old woman with feelings of sadness, despair, and tearfulness presents to her primary care physician for management. She has no prior medical or surgical history. Therapy with bupropion has begun. The treating physician must be aware of which of the following contraindications?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

A 9-year-old boy is sent for neurologic evaluation because of episodes of apparent confusion. Over the past year, the child has experienced episodes during which he develops a blank look on his face and fails to respond to questions. Moreover, it appears to take several minutes before the boy recovers from the episodes. Which one of the following best describes this patient's seizures?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Effects of morphine on CNS include all of the following EXCEPT:

Correct Answer: C

Rationale: Morphine, a mu-opioid receptor agonist, exerts profound CNS effects. Miosis (pinpoint pupils) results from parasympathetic stimulation via the Edinger-Westphal nucleus. Respiratory depression, a life-threatening effect, occurs due to reduced sensitivity of brainstem respiratory centers to CO2, a hallmark of opioid overdose. Depression of the cough reflex is mediated by medullary suppression, making morphine an antitussive. However, morphine lacks an anticonvulsant effect (choice C); it can lower the seizure threshold in overdose, potentially inducing convulsions, unlike drugs like benzodiazepines. This exception highlights morphine's CNS depressant profile, lacking the GABAergic enhancement needed for seizure control. Understanding these effects is vital for safe use, monitoring for overdose, and distinguishing morphine from anticonvulsant therapies.

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