ATI RN
Virtual ATI Pharmacology Assessment Questions
Question 1 of 5
A month after receiving a blood transfusion an immunocompromised male patient develops a fever, liver abnormalities, a rash, and diarrhea. The nurse would suspect this patient has:
Correct Answer: B
Rationale: Graft-versus-host disease (GVHD) is a potential complication in immunocompromised patients after receiving blood transfusions. It occurs when donor lymphocytes attack the recipient's tissues, leading to symptoms such as fever, rash, liver dysfunction, and diarrhea. This condition typically arises weeks to months after transfusion. An allergic response to medication would not explain the systemic symptoms. Myelosuppression is unrelated to transfusion. Therefore, GVHD is the most likely diagnosis in this scenario.
Question 2 of 5
A 45-year-old woman undergoes a complete hysterectomy for leiomyomas and dysfunctional uterine bleeding. The surgeon wants to prescribe a pain relief medication following the procedure, but the patient's serum creatinine is 1.2 mg/dL. Which of the following pain relief medications should the surgeon avoid prescribing?
Correct Answer: D
Rationale: Post-hysterectomy pain with creatinine 1.2 mg/dL (mild renal impairment) contraindicates Ketorolac , an NSAID. Its renal toxicity risks harm. Acetaminophen , Codeine , Hydrocodone , and Oxycodone (E) are safer. Ketorolac's prostaglandin inhibition could worsen kidney function.
Question 3 of 5
Jonas comes into the local blood donation center. He says he is here to donate platelets only today. The nurse knows this process is called:
Correct Answer: C
Rationale: Apheresis is the process of collecting specific blood components, such as platelets, using a specialized machine. This method allows the donor to donate only the needed component while returning the rest of the blood components back to the donor. In this case, when Jonas is donating platelets only, it is known as an apheresis donation. This process is different from the traditional whole blood donation method where all blood components are collected and separated later in a lab.
Question 4 of 5
A male patient is to begin therapy with isotretinoin and asks, 'What do I have to remember to do while taking this medicine?' How would the nurse respond? (Select all that apply.)
Correct Answer: B
Rationale: Isotretinoin is a potent medication with significant side effects and precautions. Patients should avoid sunlight (A) due to increased photosensitivity. Regular laboratory tests (C) are necessary to monitor liver function and lipid levels. Two forms of contraceptives (D) are required for females due to the high risk of teratogenicity. Monitoring weight (B) is not typically associated with isotretinoin use.
Question 5 of 5
An elderly woman took a prescription medicine to help her to sleep; however, she felt restless all night and did not sleep at all. The nurse recognizes that this woman has experienced which type of reaction or effect?
Correct Answer: B
Rationale: An idiosyncratic reaction is an unusual or unexpected response to a medication that is not related to the drug's known pharmacological effects. In this case, the elderly woman experienced restlessness instead of sedation, which is contrary to the expected effect of a sleep aid. Idiosyncratic reactions are unpredictable and can vary widely among individuals. Allergic reactions involve the immune system, mutagenic effects involve genetic changes, and synergistic effects involve interactions between multiple drugs. Since the woman's response was unexpected and not consistent with the drug's intended effect, it is classified as an idiosyncratic reaction.